Actively Recruiting

Age: 20Years +
All Genders
Healthy Volunteers
NCT05655650

Identifying Biomarkers in Alzheimer's Disease

Led by Chinese University of Hong Kong · Updated on 2022-12-19

300

Participants Needed

1

Research Sites

643 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Alzheimer's disease is a severe neurodegenerative disorder of the brain that is characterized by progressive loss of memory and cognitive decline. With the ageing population, AD is a major public health problem affecting nearly 35 million people worldwide with numbers projected to rise to 115.4 million by 2050. AD is the only cause of death among the top ten causes that has no prevention or cure . It is believed that novel treatment of AD needs to start early or even at the prodromal stage in order to be effective. Therefore, there is an urgent need to find accurate methods of early detection before patients with AD develop clinical dementia. This study aims to identify biomarkers for AD in local Chinese population. this study hypothesizes blood-based proteomics, retinal imaging, ASL-MRP and tau PET can improve the accuracy and staging of AD.

CONDITIONS

Official Title

Identifying Biomarkers in Alzheimer's Disease

Who Can Participate

Age: 20Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Chinese ethnicity
  • For dementia group, clinical diagnosis of "probable Alzheimer's disease" according to recommendations from the National Institute on Aging-Alzheimer's Association workgroups (NIA-AA)
Not Eligible

You will not qualify if you...

  • Clinical diagnosis of non-Alzheimer's disease dementia
  • Contraindication for MRI or PET scans

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Chinese University of Hong Kong

Hong Kong, Hong Hong, Hong Kong

Actively Recruiting

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Research Team

P

Pualine Kwan

CONTACT

E

Elyia Han

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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