Actively Recruiting

Phase Not Applicable
All Genders
NCT07410637

Impact of Thyroid Hormones on Human Glucose and Energy Metabolism

Led by University of Ulm · Updated on 2026-02-13

60

Participants Needed

1

Research Sites

277 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this clinical trial to clarify the impact of changes in thyroid hormone levels on glucose and lipid metabolism. Patients will be included in whom thyroid hormone levels are intentionally changed by treatment. In patients with Graves' disease, thyroid hormone levels will be lowered using medication, while in patients with thyroid cancer, thyroid hormone levels will be raised using medication. Oral glucose tolerance tests will be performed before treatment and at two time points after treatment begins to assess metabolic effects.

CONDITIONS

Official Title

Impact of Thyroid Hormones on Human Glucose and Energy Metabolism

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with an initial diagnosis of Graves' disease
  • Patients with an initial diagnosis of thyroid carcinoma
Not Eligible

You will not qualify if you...

  • Contraindications for oral glucose tolerance test
  • Diabetes mellitus
  • Fasting glucose level 63; 200 mg/dL
  • Exogenous insulin administration with action at the time of the test
  • Current disease with activation of stress hormones
  • Post-aggressive metabolism
  • Acute infectious disease

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

Ulm University Hospital

Ulm, Baden-Wurttemberg, Germany, 89081

Actively Recruiting

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Research Team

M

Martin Heni, Prof

CONTACT

R

Roza Sabia, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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