Actively Recruiting

Phase Not Applicable
Age: 21Years - 65Years
All Genders
ID07415109

Improving LDL-C Levels Through Temporal Self-regulation Theory-based, Personality-tailored Health Messages: A Three-Arm Randomized Controlled Trial

Led by National University Health System, Singapore · Updated on 2026-04-13

3000

Participants Needed

1

Research Sites

43 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate the effectiveness of personalized and general text messages on encouraging participants with high LDL cholesterol to visit their general practitioner (GP). The study runs alongside a larger study called RESET and seeks to understand if personality-tailored advice improves adherence to GP consultations compared to general messages or no intervention. Participants will receive one of three interventions embedded in their return of results emails: a personalized message tailored to their personality traits, a general health message, or no message as a control. Both message types include information on lipid therapy indications, benefits, side effects, risks of non-adherence, and lifestyle infographics. Messages are delivered only once when participants receive their LDL-C results. Participants are involved by completing two questionnaires, one before and one after receiving their results. Researchers will measure intentions to adopt healthier diets, engage in physical activity, and visit a GP over a period of three months following result return. The study monitors these outcomes without masking or blinding, with participation expected to last up to three months after results are shared.

CONDITIONS

Brief Title

Improving LDL-C Levels Through Temporal Self-regulation Theory-based, Personality-tailored Health Messages

Who Can Participate

Age: 21Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • New participants of RESET who have given consent to be contacted for future studies
  • 21 years or older
Not Eligible

You will not qualify if you...

  • Unable to read, write, or communicate in English

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or remote)

Treatment

Duration - 1 day

Participants receive a single return of results email that includes either a general health message, a personality-tailored health message, or no message depending on their assigned group.

1 baseline visit when results are returned

Follow-up

Duration - 3 months

Participants are followed for 3 months after receiving the results to assess their intentions to adopt healthier behaviors.

Assessment at 3 months post-results

Trial Site Locations

Total: 1 location

1

National University of Singapore

Singapore, Singapore, 117599

Actively Recruiting

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Research Team

J

Jocelyn Chew

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

3

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