Actively Recruiting

Age: 30Years - 95Years
All Genders
NCT06529744

Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling

Led by University Health Network, Toronto · Updated on 2025-11-20

500

Participants Needed

4

Research Sites

207 weeks

Total Duration

On this page

Sponsors

U

University Health Network, Toronto

Lead Sponsor

S

Sunnybrook Health Sciences Centre

Collaborating Sponsor

AI-Summary

What this Trial Is About

To develop a model to predict disease progression in a large cohort of patients across a variety of neurodegenerative diseases, including Mild Cognitive Impairment (MCI) and dementia due to any neurodegenerative disease, including Alzheimer's Disease (AD), Lewy Body Disease (LBD), Vascular Disease (VaD) and Frontotemporal lobar degeneration (FTLD).

CONDITIONS

Official Title

Improving Prognostic Confidence in Neurodegenerative Diseases Causing Dementia Using Peripheral Biomarkers and Integrative Modeling

Who Can Participate

Age: 30Years - 95Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Possible or probable diagnosis of mild cognitive impairment or early dementia
  • Age between 30 and 95 years
  • Have a study partner who has weekly contact with you
  • Able to complete most study procedures as judged by the study team
Not Eligible

You will not qualify if you...

  • Unable to complete most assessments as judged by the principal investigator
  • Symptoms believed by the investigator to be caused by conditions other than neurodegeneration, despite exclusionary conditions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Baycrest

North York, Ontario, Canada, M6A 2E1

Not Yet Recruiting

2

Sunnybrook Health Sciences Centre

Toronto, Ontario, Canada, M4N 3M5

Not Yet Recruiting

3

Toronto Western Hospital, University Health Network

Toronto, Ontario, Canada, M5T 2S8

Actively Recruiting

4

Centre for Addiction and Mental Health

Toronto, Ontario, Canada, M6J 1H1

Not Yet Recruiting

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Research Team

C

Claudia Clementi, HBSc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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