Actively Recruiting
A Phase III Study of Induction Pembrolizumab and Chemotherapy Followed by Chemoradiation and Pembrolizumab Versus Chemoradiation and Pembrolizumab Both Followed by Pembrolizumab for High Risk Locally Advanced Cervical Cancer
Led by National Cancer Institute (NCI) · Updated on 2026-06-05
336
Participants Needed
253
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying high-risk locally advanced cervical cancer that has spread to nearby tissue or lymph nodes. This trial compares adding induction chemotherapy with carboplatin, paclitaxel, and pembrolizumab before standard treatment, versus standard chemoradiation with pembrolizumab followed by pembrolizumab maintenance. The goal is to see if adding induction therapy improves progression-free survival and overall survival, while also assessing treatment side effects and biomarkers related to outcomes. Participants are randomly assigned to one of two groups. One group receives standard chemoradiation with cisplatin and pembrolizumab alongside radiation therapy, followed by pembrolizumab maintenance. The other group receives induction chemotherapy with carboplatin, paclitaxel, and pembrolizumab for two cycles before starting chemoradiation plus pembrolizumab and then pembrolizumab maintenance. Radiation is given daily for several weeks followed by brachytherapy treatments. The study includes blood tests, PET, CT, chest x-rays, and MRI scans throughout. Participants will be monitored with scans and blood samples during treatment and followed every three months for two years, then every six months for three more years. Researchers measure progression-free survival as the main outcome, along with overall survival, treatment side effects, treatment completion times, and biomarker changes. Safety and response to therapy are closely tracked for up to seven years after randomization.
CONDITIONS
Brief Title
Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients must have newly diagnosed cervical cancer confirmed by pathology, including squamous cell carcinoma, adenocarcinoma, or adenosquamous carcinoma
- Patients must have locally advanced cervical cancer stage IIIA, IIIB, IIIC1, IIIC2, or IVA without paraaortic lymph node metastases above T12/L1
- No prior definitive surgery, radiation, systemic therapy, or immunotherapy for cervical cancer
- Age 18 years or older
- ECOG performance status of 0, 1, or 2
- Not pregnant and not nursing
- Adequate blood counts: ANC 63 1,500 cells/mm3, platelets 63 100,000 cells/mm3, hemoglobin 63 8 g/dl
- Creatinine clearance of 63 50 mL/min by Cockcroft-Gault formula
- Total bilirubin 64 1.5 times institutional upper limit of normal (ULN), or 64 3 times ULN if Gilbert's disease
- AST and ALT 64 3 times institutional ULN
- Cardiac function class 2B or better by NYHA Functional Classification
- No active infection requiring intravenous antibiotics
- No live vaccine within 30 days prior to registration
- No immunodeficiency or recent immunosuppressive therapy
- No active autoimmune disease requiring systemic treatment in past 2 years
- No history of pneumonitis requiring steroids or current pneumonitis
- No allergic reaction history to study agents or similar compounds
You will not qualify if you...
- Prior hysterectomy involving removal of entire uterus
- Paraaortic lymph node metastases above T12/L1
- Previous treatment for cervical cancer including surgery, radiation, systemic therapy, or immunotherapy
- Pregnant or nursing women
- ECOG performance status greater than 2
- Active infections requiring parenteral antibiotics
- Live vaccination within 30 days before registration
- Immunodeficiency or recent use of systemic immunosuppressants exceeding 10 mg prednisone equivalent daily within 7 days
- Active autoimmune disease requiring systemic treatment in past 2 years
- History of non-infectious pneumonitis requiring steroids or current pneumonitis
- Known allergic reactions to the study agents or related compounds
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 6 weeks
Participants in Arm 2 receive induction therapy with carboplatin and paclitaxel intravenously weekly for 3 weeks and pembrolizumab intravenously every 3 weeks for 2 cycles before starting chemoradiation.
Weekly visits for 3 weeks and pembrolizumab infusion visits every 3 weeks during induction
Duration - 5 to 7 weeks
Participants undergo chemoradiation treatment consisting of weekly cisplatin intravenously for 5 weeks, pembrolizumab intravenously every 3 weeks for 5 doses, and daily radiation therapy 5 days per week for 25-29 treatments followed by brachytherapy up to twice per week for 4-5 treatments.
Weekly cisplatin and pembrolizumab infusion visits; daily radiation therapy visits 5 days per week; up to 10 brachytherapy visits over 2-3 weeks
Duration - Up to approximately 84 weeks
Participants receive pembrolizumab intravenously every 6 weeks for up to 14 or 15 cycles in the absence of disease progression or unacceptable toxicity.
Pembrolizumab infusion visits every 6 weeks for up to 14 to 15 cycles
Duration - Up to 5 years
After completing study treatment, participants are followed up to monitor their health and disease status with visits every 3 months for 2 years, then every 6 months for 3 additional years.
Follow-up visits every 3 months for 2 years, then every 6 months for 3 years
Trial Site Locations
Total: 253 locations
1
University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, United States, 35233
Not Yet Recruiting
2
Highlands Oncology Group - Fayetteville
Fayetteville, Arkansas, United States, 72703
Actively Recruiting
3
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States, 72205
Actively Recruiting
4
Highlands Oncology Group - Rogers
Rogers, Arkansas, United States, 72758
Actively Recruiting
5
Highlands Oncology Group
Springdale, Arkansas, United States, 72762
Actively Recruiting
6
Kaiser Permanente-Bellflower
Bellflower, California, United States, 90706
Actively Recruiting
7
City of Hope Corona
Corona, California, United States, 92882
Actively Recruiting
8
City of Hope Comprehensive Cancer Center
Duarte, California, United States, 91010
Actively Recruiting
9
Kaiser Permanente South Bay
Harbor City, California, United States, 90710
Actively Recruiting
10
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care
Irvine, California, United States, 92612
Actively Recruiting
11
City of Hope at Irvine Lennar
Irvine, California, United States, 92618
Actively Recruiting
12
Kaiser Permanente-Irvine
Irvine, California, United States, 92618
Actively Recruiting
13
UC San Diego Moores Cancer Center
La Jolla, California, United States, 92093
Actively Recruiting
14
City of Hope Antelope Valley
Lancaster, California, United States, 93534
Suspended
15
Kaiser Permanente Los Angeles Medical Center
Los Angeles, California, United States, 90027
Actively Recruiting
16
Kaiser Permanente West Los Angeles
Los Angeles, California, United States, 90034
Actively Recruiting
17
UC Irvine Health/Chao Family Comprehensive Cancer Center
Orange, California, United States, 92868
Actively Recruiting
18
Kaiser Permanente - Panorama City
Panorama City, California, United States, 91402
Actively Recruiting
19
Kaiser Permanente-San Diego Zion
San Diego, California, United States, 92120
Actively Recruiting
20
Kaiser Permanente-San Marcos
San Marcos, California, United States, 92078
Actively Recruiting
21
City of Hope South Pasadena
South Pasadena, California, United States, 91030
Actively Recruiting
22
City of Hope Upland
Upland, California, United States, 91786
Actively Recruiting
23
Kaiser Permanente-Woodland Hills
Woodland Hills, California, United States, 91367
Actively Recruiting
24
UCHealth University of Colorado Hospital
Aurora, Colorado, United States, 80045
Actively Recruiting
25
UCHealth Highlands Ranch Hospital
Highlands Ranch, Colorado, United States, 80129
Actively Recruiting
26
Danbury Hospital
Danbury, Connecticut, United States, 06810
Actively Recruiting
27
Norwalk Hospital
Norwalk, Connecticut, United States, 06856
Actively Recruiting
28
Beebe South Coastal Health Campus
Millville, Delaware, United States, 19967
Actively Recruiting
29
Helen F Graham Cancer Center
Newark, Delaware, United States, 19713
Actively Recruiting
30
Medical Oncology Hematology Consultants PA
Newark, Delaware, United States, 19713
Actively Recruiting
31
Beebe Health Campus
Rehoboth Beach, Delaware, United States, 19971
Actively Recruiting
32
UM Sylvester Comprehensive Cancer Center at Coral Gables
Coral Gables, Florida, United States, 33146
Actively Recruiting
33
UM Sylvester Comprehensive Cancer Center at Coral Springs
Coral Springs, Florida, United States, 33065
Actively Recruiting
34
UM Sylvester Comprehensive Cancer Center at Deerfield Beach
Deerfield Beach, Florida, United States, 33442
Actively Recruiting
35
UM Sylvester Comprehensive Cancer Center at Doral
Doral, Florida, United States, 33166
Actively Recruiting
36
Broward Health Medical Center
Fort Lauderdale, Florida, United States, 33316
Actively Recruiting
37
Memorial Regional Hospital/Joe DiMaggio Children's Hospital
Hollywood, Florida, United States, 33021
Actively Recruiting
38
UM Sylvester Comprehensive Cancer Center at Hollywood
Hollywood, Florida, United States, 33021
Actively Recruiting
39
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, United States, 33136
Actively Recruiting
40
UM Sylvester Comprehensive Cancer Center at Kendall
Miami, Florida, United States, 33176
Actively Recruiting
41
University of Miami Sylvester Comprehensive Cancer Center at Sole Mia
North Miami, Florida, United States, 33181
Actively Recruiting
42
Orlando Health Cancer Institute
Orlando, Florida, United States, 32806
Actively Recruiting
43
Memorial Hospital West
Pembroke Pines, Florida, United States, 33028
Actively Recruiting
44
UM Sylvester Comprehensive Cancer Center at Plantation
Plantation, Florida, United States, 33324
Actively Recruiting
45
Moffitt Cancer Center at SouthShore
Ruskin, Florida, United States, 33570
Actively Recruiting
46
Moffitt Cancer Center-International Plaza
Tampa, Florida, United States, 33607
Actively Recruiting
47
Moffitt Cancer Center - McKinley Campus
Tampa, Florida, United States, 33612
Actively Recruiting
48
Moffitt Cancer Center
Tampa, Florida, United States, 33612
Actively Recruiting
49
Moffitt Cancer Center at Wesley Chapel
Wesley Chapel, Florida, United States, 33544
Actively Recruiting
50
Emory University Hospital Midtown
Atlanta, Georgia, United States, 30308
Actively Recruiting
51
Piedmont Hospital
Atlanta, Georgia, United States, 30309
Actively Recruiting
52
Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia, United States, 30322
Actively Recruiting
53
Emory Decatur Hospital
Decatur, Georgia, United States, 30033
Actively Recruiting
54
CTCA at Southeastern Regional Medical Center
Newnan, Georgia, United States, 30265
Actively Recruiting
55
Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho, United States, 83706
Actively Recruiting
56
Saint Luke's Cancer Institute - Boise
Boise, Idaho, United States, 83712
Actively Recruiting
57
Saint Alphonsus Cancer Care Center-Caldwell
Caldwell, Idaho, United States, 83605
Actively Recruiting
58
Kootenai Health - Coeur d'Alene
Coeur d'Alene, Idaho, United States, 83814
Suspended
59
Saint Luke's Cancer Institute - Fruitland
Fruitland, Idaho, United States, 83619
Actively Recruiting
60
Saint Luke's Cancer Institute - Meridian
Meridian, Idaho, United States, 83642
Actively Recruiting
61
Saint Alphonsus Cancer Care Center-Nampa
Nampa, Idaho, United States, 83687
Actively Recruiting
62
Saint Luke's Cancer Institute - Nampa
Nampa, Idaho, United States, 83687
Actively Recruiting
63
Kootenai Clinic Cancer Services - Post Falls
Post Falls, Idaho, United States, 83854
Suspended
64
Northwestern University
Chicago, Illinois, United States, 60611
Actively Recruiting
65
Rush MD Anderson Cancer Center
Chicago, Illinois, United States, 60612
Actively Recruiting
66
Carle at The Riverfront
Danville, Illinois, United States, 61832
Actively Recruiting
67
Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois, United States, 62526
Actively Recruiting
68
Decatur Memorial Hospital
Decatur, Illinois, United States, 62526
Actively Recruiting
69
Northwestern Medicine Cancer Center Kishwaukee
DeKalb, Illinois, United States, 60115
Actively Recruiting
70
Carle Physician Group-Effingham
Effingham, Illinois, United States, 62401
Actively Recruiting
71
Crossroads Cancer Center
Effingham, Illinois, United States, 62401
Suspended
72
Northwestern Medicine Cancer Center Delnor
Geneva, Illinois, United States, 60134
Actively Recruiting
73
Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois, United States, 61938
Actively Recruiting
74
Loyola University Medical Center
Maywood, Illinois, United States, 60153
Actively Recruiting
75
Northwestern Medicine Oak Brook
Oak Brook, Illinois, United States, 60523
Actively Recruiting
76
Northwestern Medicine Orland Park
Orland Park, Illinois, United States, 60462
Actively Recruiting
77
UW Health Carbone Cancer Center Rockford
Rockford, Illinois, United States, 61114
Actively Recruiting
78
Southern Illinois University School of Medicine
Springfield, Illinois, United States, 62702
Actively Recruiting
79
Springfield Clinic
Springfield, Illinois, United States, 62702
Actively Recruiting
80
Springfield Memorial Hospital
Springfield, Illinois, United States, 62781
Actively Recruiting
81
Carle Cancer Center
Urbana, Illinois, United States, 61801
Actively Recruiting
82
Northwestern Medicine Cancer Center Warrenville
Warrenville, Illinois, United States, 60555
Actively Recruiting
83
Midwestern Regional Medical Center
Zion, Illinois, United States, 60099
Actively Recruiting
84
Parkview Regional Medical Center
Fort Wayne, Indiana, United States, 46845
Actively Recruiting
85
UI Health Care Mission Cancer and Blood - Ankeny Clinic
Ankeny, Iowa, United States, 50023
Actively Recruiting
86
Mercy Hospital
Cedar Rapids, Iowa, United States, 52403
Actively Recruiting
87
Oncology Associates at Mercy Medical Center
Cedar Rapids, Iowa, United States, 52403
Actively Recruiting
88
UI Health Care Mission Cancer and Blood - West Des Moines Clinic
Clive, Iowa, United States, 50325
Actively Recruiting
89
Iowa Methodist Medical Center
Des Moines, Iowa, United States, 50309
Actively Recruiting
90
UI Health Care Mission Cancer and Blood - Des Moines Clinic
Des Moines, Iowa, United States, 50309
Actively Recruiting
91
Mercy Medical Center - Des Moines
Des Moines, Iowa, United States, 50314
Actively Recruiting
92
UI Health Care Mission Cancer and Blood - Laurel Clinic
Des Moines, Iowa, United States, 50314
Actively Recruiting
93
University of Iowa/Holden Comprehensive Cancer Center
Iowa City, Iowa, United States, 52242
Actively Recruiting
94
UI Health Care Mission Cancer and Blood - Waukee Clinic
Waukee, Iowa, United States, 50263
Actively Recruiting
95
University of Kansas Cancer Center
Kansas City, Kansas, United States, 66160
Actively Recruiting
96
University of Kansas Cancer Center-Overland Park
Overland Park, Kansas, United States, 66210
Actively Recruiting
97
University of Kansas Hospital-Indian Creek Campus
Overland Park, Kansas, United States, 66211
Actively Recruiting
98
University of Kansas Hospital-Westwood Cancer Center
Westwood, Kansas, United States, 66205
Actively Recruiting
99
University of Kentucky/Markey Cancer Center
Lexington, Kentucky, United States, 40536
Actively Recruiting
100
West Jefferson Medical Center
Marrero, Louisiana, United States, 70072
Actively Recruiting
101
East Jefferson General Hospital
Metairie, Louisiana, United States, 70006
Actively Recruiting
102
LSU Healthcare Network / Metairie Multi-Specialty Clinic
Metairie, Louisiana, United States, 70006
Actively Recruiting
103
University Medical Center New Orleans
New Orleans, Louisiana, United States, 70112
Actively Recruiting
104
Ochsner Baptist Medical Center
New Orleans, Louisiana, United States, 70115
Actively Recruiting
105
Ochsner Medical Center Jefferson
New Orleans, Louisiana, United States, 70121
Actively Recruiting
106
MaineHealth Coastal Cancer Treatment Center
Bath, Maine, United States, 04530
Actively Recruiting
107
MaineHealth Maine Medical Center - Portland
Portland, Maine, United States, 04102
Actively Recruiting
108
MaineHealth Cancer Care Center of York County
Sanford, Maine, United States, 04073
Actively Recruiting
109
MaineHealth Maine Medical Center- Scarborough
Scarborough, Maine, United States, 04074
Actively Recruiting
110
Trinity Health Medical Center - Brighton
Brighton, Michigan, United States, 48114
Actively Recruiting
111
Bronson Methodist Hospital
Kalamazoo, Michigan, United States, 49007
Actively Recruiting
112
West Michigan Cancer Center
Kalamazoo, Michigan, United States, 49007
Actively Recruiting
113
Trinity Health Saint Joseph Mercy Oakland Hospital
Pontiac, Michigan, United States, 48341
Suspended
114
Freeman Health System
Joplin, Missouri, United States, 64804
Actively Recruiting
115
University of Kansas Cancer Center - Briarcliff
Kansas City, Missouri, United States, 64116
Actively Recruiting
116
University of Kansas Cancer Center - North
Kansas City, Missouri, United States, 64154
Actively Recruiting
117
University of Kansas Cancer Center - Lee's Summit
Lee's Summit, Missouri, United States, 64064
Actively Recruiting
118
Phelps Health Delbert Day Cancer Institute
Rolla, Missouri, United States, 65401
Actively Recruiting
119
Mercy Hospital Springfield
Springfield, Missouri, United States, 65804
Actively Recruiting
120
Mercy Hospital Saint Louis
St Louis, Missouri, United States, 63141
Actively Recruiting
121
Billings Clinic Cancer Center
Billings, Montana, United States, 59101
Actively Recruiting
122
Community Medical Center
Missoula, Montana, United States, 59804
Suspended
123
Nebraska Methodist Hospital
Omaha, Nebraska, United States, 68114
Actively Recruiting
124
University of Nebraska Medical Center
Omaha, Nebraska, United States, 68198
Actively Recruiting
125
Women's Cancer Center of Nevada
Las Vegas, Nevada, United States, 89106
Actively Recruiting
126
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
Lebanon, New Hampshire, United States, 03756
Actively Recruiting
127
Memorial Sloan Kettering Basking Ridge
Basking Ridge, New Jersey, United States, 07920
Actively Recruiting
128
Cooper Hospital University Medical Center
Camden, New Jersey, United States, 08103
Actively Recruiting
129
Jersey City Medical Center
Jersey City, New Jersey, United States, 07302
Actively Recruiting
130
Memorial Sloan Kettering Monmouth
Middletown, New Jersey, United States, 07748
Actively Recruiting
131
Memorial Sloan Kettering Bergen
Montvale, New Jersey, United States, 07645
Actively Recruiting
132
Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, United States, 08903
Actively Recruiting
133
Rutgers New Jersey Medical School
Newark, New Jersey, United States, 07101
Actively Recruiting
134
Capital Health Medical Center-Hopewell
Pennington, New Jersey, United States, 08534
Actively Recruiting
135
University of New Mexico Cancer Center
Albuquerque, New Mexico, United States, 87106
Actively Recruiting
136
Northwell Health Imbert Cancer Center
Bay Shore, New York, United States, 11706
Actively Recruiting
137
Roswell Park Cancer Institute
Buffalo, New York, United States, 14263
Actively Recruiting
138
Memorial Sloan Kettering Commack
Commack, New York, United States, 11725
Actively Recruiting
139
Northwell Health Physician Partners at Flushing
Flushing, New York, United States, 11354
Actively Recruiting
140
Northwell Health Physicians Partners Radiation Medicine at Queens
Forest Hills, New York, United States, 11375
Actively Recruiting
141
Northwell Health Cancer Institute at Huntington
Greenlawn, New York, United States, 11740
Actively Recruiting
142
Memorial Sloan Kettering Westchester
Harrison, New York, United States, 10604
Actively Recruiting
143
Northwell Health/Center for Advanced Medicine
Lake Success, New York, United States, 11042
Actively Recruiting
144
NYU Langone Hospital - Long Island
Mineola, New York, United States, 11501
Actively Recruiting
145
Northern Westchester Hospital
Mount Kisco, New York, United States, 10549
Actively Recruiting
146
Mount Sinai Chelsea
New York, New York, United States, 10011
Actively Recruiting
147
Laura and Isaac Perlmutter Cancer Center at NYU Langone
New York, New York, United States, 10016
Actively Recruiting
148
Mount Sinai Hospital
New York, New York, United States, 10029
Actively Recruiting
149
Manhattan Eye Ear and Throat Hospital
New York, New York, United States, 10065
Actively Recruiting
150
Memorial Sloan Kettering Cancer Center
New York, New York, United States, 10065
Actively Recruiting
151
Lenox Hill Hospital
New York, New York, United States, 10075
Actively Recruiting
152
Upstate Cancer Center Radiation Oncology at Oswego
Oswego, New York, United States, 13126
Actively Recruiting
153
Queens Cancer Center
Rego Park, New York, United States, 11374
Actively Recruiting
154
Phelps Memorial Hospital Center
Sleepy Hollow, New York, United States, 10591
Actively Recruiting
155
Stony Brook University Medical Center
Stony Brook, New York, United States, 11794
Actively Recruiting
156
State University of New York Upstate Medical University
Syracuse, New York, United States, 13210
Actively Recruiting
157
Upstate Cancer Center at Hill Radiation Oncology
Syracuse, New York, United States, 13210
Actively Recruiting
158
Montefiore Medical Center-Einstein Campus
The Bronx, New York, United States, 10461
Actively Recruiting
159
Montefiore Medical Center-Weiler Hospital
The Bronx, New York, United States, 10461
Suspended
160
Montefiore Medical Center - Moses Campus
The Bronx, New York, United States, 10467
Actively Recruiting
161
Memorial Sloan Kettering Nassau
Uniondale, New York, United States, 11553
Actively Recruiting
162
Upstate Cancer Center at Verona
Verona, New York, United States, 13478
Actively Recruiting
163
UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, United States, 27599
Actively Recruiting
164
Carolinas Medical Center/Levine Cancer Institute
Charlotte, North Carolina, United States, 28203
Actively Recruiting
165
Novant Health Presbyterian Medical Center
Charlotte, North Carolina, United States, 28204
Actively Recruiting
166
Atrium Health Cabarrus/LCI-Concord
Concord, North Carolina, United States, 28025
Actively Recruiting
167
Duke University Medical Center
Durham, North Carolina, United States, 27710
Actively Recruiting
168
Levine Cancer Institute-Gaston
Gastonia, North Carolina, United States, 28054
Actively Recruiting
169
Duke Women's Cancer Care Raleigh
Raleigh, North Carolina, United States, 27607
Actively Recruiting
170
UHHS-Chagrin Highlands Medical Center
Beachwood, Ohio, United States, 44122
Actively Recruiting
171
Aultman Health Foundation
Canton, Ohio, United States, 44710
Actively Recruiting
172
Miami Valley Hospital South
Centerville, Ohio, United States, 45459
Actively Recruiting
173
Geauga Hospital
Chardon, Ohio, United States, 44024
Actively Recruiting
174
University of Cincinnati Cancer Center-UC Medical Center
Cincinnati, Ohio, United States, 45219
Actively Recruiting
175
Case Western Reserve University
Cleveland, Ohio, United States, 44106
Actively Recruiting
176
Cleveland Clinic Foundation
Cleveland, Ohio, United States, 44195
Actively Recruiting
177
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States, 43210
Actively Recruiting
178
Miami Valley Hospital
Dayton, Ohio, United States, 45409
Actively Recruiting
179
Miami Valley Hospital North
Dayton, Ohio, United States, 45415
Actively Recruiting
180
Atrium Medical Center-Middletown Regional Hospital
Franklin, Ohio, United States, 45005-1066
Actively Recruiting
181
Miami Valley Cancer Care and Infusion
Greenville, Ohio, United States, 45331
Actively Recruiting
182
Hillcrest Hospital Cancer Center
Mayfield Heights, Ohio, United States, 44124
Actively Recruiting
183
UH Seidman Cancer Center at Lake Health Mentor Campus
Mentor, Ohio, United States, 44060
Actively Recruiting
184
University Hospitals Parma Medical Center
Parma, Ohio, United States, 44129
Actively Recruiting
185
ProMedica Flower Hospital
Sylvania, Ohio, United States, 43560
Actively Recruiting
186
Upper Valley Medical Center
Troy, Ohio, United States, 45373
Actively Recruiting
187
University of Cincinnati Cancer Center-West Chester
West Chester, Ohio, United States, 45069
Actively Recruiting
188
UH Seidman Cancer Center at Saint John Medical Center
Westlake, Ohio, United States, 44145
Actively Recruiting
189
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, United States, 73104
Actively Recruiting
190
Oklahoma Cancer Specialists and Research Institute-Tulsa
Tulsa, Oklahoma, United States, 74146
Actively Recruiting
191
Clackamas Radiation Oncology Center
Clackamas, Oregon, United States, 97015
Actively Recruiting
192
Providence Newberg Medical Center
Newberg, Oregon, United States, 97132
Actively Recruiting
193
Providence Willamette Falls Medical Center
Oregon City, Oregon, United States, 97045
Actively Recruiting
194
Legacy Good Samaritan Hospital and Medical Center
Portland, Oregon, United States, 97210
Actively Recruiting
195
Providence Portland Medical Center
Portland, Oregon, United States, 97213
Actively Recruiting
196
Providence Saint Vincent Medical Center
Portland, Oregon, United States, 97225
Actively Recruiting
197
Kaiser Permanente Northwest
Portland, Oregon, United States, 97227
Actively Recruiting
198
Oregon Health and Science University
Portland, Oregon, United States, 97239
Actively Recruiting
199
Legacy Meridian Park Hospital
Tualatin, Oregon, United States, 97062
Actively Recruiting
200
Lehigh Valley Hospital-Cedar Crest
Allentown, Pennsylvania, United States, 18103
Actively Recruiting
201
Saint Luke's Cancer Center - Allentown
Allentown, Pennsylvania, United States, 18104
Actively Recruiting
202
Saint Luke's University Hospital-Bethlehem Campus
Bethlehem, Pennsylvania, United States, 18015
Actively Recruiting
203
Lehigh Valley Hospital - Muhlenberg
Bethlehem, Pennsylvania, United States, 18017
Actively Recruiting
204
Geisinger Medical Center
Danville, Pennsylvania, United States, 17822
Actively Recruiting
205
Pocono Medical Center
East Stroudsburg, Pennsylvania, United States, 18301
Actively Recruiting
206
Saint Luke's Hospital-Anderson Campus
Easton, Pennsylvania, United States, 18045
Actively Recruiting
207
UPMC Hillman Cancer Center Erie
Erie, Pennsylvania, United States, 16505
Actively Recruiting
208
UPMC Cancer Centers - Arnold Palmer Pavilion
Greensburg, Pennsylvania, United States, 15601
Actively Recruiting
209
UPMC Pinnacle Cancer Center/Community Osteopathic Campus
Harrisburg, Pennsylvania, United States, 17109
Actively Recruiting
210
Penn State Milton S Hershey Medical Center
Hershey, Pennsylvania, United States, 17033-0850
Actively Recruiting
211
IRMC Cancer Center
Indiana, Pennsylvania, United States, 15701
Actively Recruiting
212
Geisinger Medical Oncology-Lewisburg
Lewisburg, Pennsylvania, United States, 17837
Actively Recruiting
213
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
Mechanicsburg, Pennsylvania, United States, 17050
Actively Recruiting
214
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, United States, 19107
Actively Recruiting
215
Fox Chase Cancer Center
Philadelphia, Pennsylvania, United States, 19111
Actively Recruiting
216
Temple University Hospital
Philadelphia, Pennsylvania, United States, 19140
Actively Recruiting
217
UPMC-Magee Womens Hospital
Pittsburgh, Pennsylvania, United States, 15213
Actively Recruiting
218
UPMC-Passavant Hospital
Pittsburgh, Pennsylvania, United States, 15237
Actively Recruiting
219
Saint Luke's Hospital - Upper Bucks Campus
Quakertown, Pennsylvania, United States, 18951
Actively Recruiting
220
UPMC Cancer Center at UPMC Northwest
Seneca, Pennsylvania, United States, 16346
Actively Recruiting
221
Saint Luke's Hospital - Monroe Campus
Stroudsburg, Pennsylvania, United States, 18360
Actively Recruiting
222
Geisinger Wyoming Valley/Henry Cancer Center
Wilkes-Barre, Pennsylvania, United States, 18711
Actively Recruiting
223
Asplundh Cancer Pavilion
Willow Grove, Pennsylvania, United States, 19090
Actively Recruiting
224
Women and Infants Hospital
Providence, Rhode Island, United States, 02905
Actively Recruiting
225
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
Actively Recruiting
226
Gibbs Cancer Center-Gaffney
Gaffney, South Carolina, United States, 29341
Actively Recruiting
227
Gibbs Cancer Center-Pelham
Greer, South Carolina, United States, 29651
Actively Recruiting
228
Spartanburg Medical Center
Spartanburg, South Carolina, United States, 29303
Actively Recruiting
229
Avera Cancer Institute
Sioux Falls, South Dakota, United States, 57105
Actively Recruiting
230
Parkland Memorial Hospital
Dallas, Texas, United States, 75235
Actively Recruiting
231
UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas, United States, 75390
Actively Recruiting
232
UT Southwestern/Simmons Cancer Center-Fort Worth
Fort Worth, Texas, United States, 76104
Actively Recruiting
233
UT Southwestern Clinical Center at Richardson/Plano
Richardson, Texas, United States, 75080
Actively Recruiting
234
Farmington Health Center
Farmington, Utah, United States, 84025
Actively Recruiting
235
University of Utah Sugarhouse Health Center
Salt Lake City, Utah, United States, 84106
Actively Recruiting
236
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, United States, 84112
Actively Recruiting
237
Inova Alexandria Hospital
Alexandria, Virginia, United States, 22304
Actively Recruiting
238
University of Virginia Cancer Center
Charlottesville, Virginia, United States, 22908
Actively Recruiting
239
Inova Schar Cancer Institute
Fairfax, Virginia, United States, 22031
Actively Recruiting
240
Inova Fair Oaks Hospital
Fairfax, Virginia, United States, 22033
Actively Recruiting
241
Inova Fairfax Hospital
Falls Church, Virginia, United States, 22042
Actively Recruiting
242
Inova Loudoun Hospital
Leesburg, Virginia, United States, 20176
Actively Recruiting
243
VCU Massey Comprehensive Cancer Center
Richmond, Virginia, United States, 23298
Actively Recruiting
244
Carilion Roanoke Memorial Hospital
Roanoke, Virginia, United States, 24033
Actively Recruiting
245
Legacy Salmon Creek Hospital
Vancouver, Washington, United States, 98686
Actively Recruiting
246
West Virginia University Healthcare
Morgantown, West Virginia, United States, 26506
Actively Recruiting
247
Camden Clark Medical Center
Parkersburg, West Virginia, United States, 26101
Actively Recruiting
248
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
Madison, Wisconsin, United States, 53718
Actively Recruiting
249
University of Wisconsin Carbone Cancer Center - University Hospital
Madison, Wisconsin, United States, 53792
Actively Recruiting
250
Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53226
Actively Recruiting
251
ProHealth D N Greenwald Center
Mukwonago, Wisconsin, United States, 53149
Actively Recruiting
252
ProHealth Oconomowoc Memorial Hospital
Oconomowoc, Wisconsin, United States, 53066
Actively Recruiting
253
UW Cancer Center at ProHealth Care
Waukesha, Wisconsin, United States, 53188
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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