Actively Recruiting
Integration of Stepped Care for Perinatal Mood and Anxiety Disorders Among Women Attending MCH Clinics
Led by Kenyatta National Hospital · Updated on 2025-12-10
2970
Participants Needed
2
Research Sites
158 weeks
Total Duration
On this page
Sponsors
K
Kenyatta National Hospital
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Perinatal mood and anxiety disorders (PMAD), defined as depression and anxiety during pregnancy or up to 1 year postpartum, account for substantial morbidity and mortality among birthing people globally especially in low- and middle-income countries. Several evidence-based interventions are recommended for identification and management of PMAD by non-specialist providers in resource-limited settings. This cluster-randomized trial seeks to evaluate the effect of a stepped-care intervention for screening and treatment of PMAD among perinatal women, on clinical and implementation outcomes.
CONDITIONS
Official Title
Integration of Stepped Care for Perinatal Mood and Anxiety Disorders Among Women Attending MCH Clinics
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pregnant and at least 28 weeks gestation
- Attending antenatal care at the facility
- 14 years old or older
- Screen positive for perinatal mood and anxiety disorder symptoms (PHQ-2 score 3 or more and/or GAD-2 score 3 or more)
- Willing to return to the maternal and child health and PMTCT clinic for study visits
You will not qualify if you...
- Less than 28 weeks gestation
- High risk of self-harm based on study assessment
- Cognitive impairments or psychotic symptoms
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Kenyatta National Hospital
Nairobi, Kenya
Actively Recruiting
2
HomaBay, Siaya and Kisumu
Western Kenya, Kenya
Actively Recruiting
Research Team
N
Nancy Ngumbau, MBChB, MPH
CONTACT
A
Agnes Karume, MBChB, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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