Unfractionated heparin-clopidogrel combination in ST-elevation myocardial infarction not receiving reperfusion therapy.
Raffaele Bugiardini, Maria Dorobantu, Zorana Vasiljevic...
https://pubmed.ncbi.nlm.nih.gov/25988359Actively Recruiting
Age: 18Years +
All Genders
ID01218776
International Survey of Acute Coronary Syndromes
Led by University of Bologna · Updated on 2025-04-16
36000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are conducting the International Survey of Acute Coronary Syndromes (ISACS), an observational study designed to collect and analyze data from patients with acute coronary syndromes such as STEMI or NSTEMI. The study aims to document patient characteristics, in-hospital outcomes, and longer-term results at 6 months and 1 year. It also assesses invasive procedures, complications, and how well treatments follow established guidelines internationally. This study is non-interventional and serves as a patient registry. It collects detailed information from participating centers on treatment regimens and procedures without administering any specific therapies. The study covers both retrospective and prospective data gathering, focusing on outcomes and adherence to recommended care practices across multiple countries. Participants provide data through hospital records and follow-up evaluations at 30 days, 6 months, and 1 year. Researchers measure outcomes including all-cause mortality, cardiovascular deaths, recurrent heart attacks, and genetic studies related to clinical results. Adherence to guideline-recommended therapies is also monitored. The study is led by the University of Bologna and involves various international collaborators, with patient participation lasting up to one year after initial admission.
CONDITIONS
Brief Title
International Survey of Acute Coronary Syndromes
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Diagnosis of acute coronary syndromes such as STEMI or NSTEMI
You will not qualify if you...
- Under 18 years of age
- Unable to give informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Diagnostic Evaluation
Duration - Hospital stay duration
Participants diagnosed with acute coronary syndromes such as STEMI or NSTEMI are documented including invasive procedures and complications.
1 hospital admission visit
Surveillance
Duration - Up to 1 year
Participants are observed to document in-hospital outcomes and outcomes at 6 months and 1 year including mortality, recurrent myocardial infarction, and adherence to guideline-recommended therapies.
Visits or contacts at discharge, 6 months, and 1 year
Trial Site Locations
Total: 1 location
1
University of Bologna
Bologna, Emilia-Romagna, Italy, 40138
Actively Recruiting
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Research Team
R
Raffaele Bugiardini, MD
L
Lina Badimon, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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Published Research Related To This Trial
Comparison of Early Versus Delayed Oral β Blockers in Acute Coronary Syndromes and Effect on Outcomes.
Raffaele Bugiardini, Edina Cenko, Beatrice Ricci...
https://pubmed.ncbi.nlm.nih.gov/26778165Reperfusion therapy for ST-elevation acute myocardial infarction in Eastern Europe: the ISACS-TC registry.
Edina Cenko, Beatrice Ricci, Sasko Kedev...
https://pubmed.ncbi.nlm.nih.gov/29474588Association between comorbidities and absence of chest pain in acute coronary syndrome with in-hospital outcome.
Olivia Manfrini, Beatrice Ricci, Edina Cenko...
https://pubmed.ncbi.nlm.nih.gov/27381858Factors associated with use of percutaneous coronary intervention among elderly patients presenting with ST segment elevation acute myocardial infarction (STEMI): Results from the ISACS-TC registry.
Lucian Câlmâc, Vlad Bătăilă, Beatrice Ricci...
https://pubmed.ncbi.nlm.nih.gov/27381859The International Survey of Acute Coronary Syndromes in Transitional Countries (ISACS-TC): 2010-2015.
Raffaele Bugiardini, Lina Badimon, ISACS-TC Investigators and Coordinators
https://pubmed.ncbi.nlm.nih.gov/27386758The no-reflow phenomenon in the young and in the elderly.
Edina Cenko, Beatrice Ricci, Sasko Kedev...
https://pubmed.ncbi.nlm.nih.gov/27499222Primary percutaneous coronary intervention in octogenarians.
Beatrice Ricci, Olivia Manfrini, Edina Cenko...
https://pubmed.ncbi.nlm.nih.gov/27506888Invasive versus conservative strategy in acute coronary syndromes: The paradox in women's outcomes.
Edina Cenko, Beatrice Ricci, Sasko Kedev...
https://pubmed.ncbi.nlm.nih.gov/27514628Delayed Care and Mortality Among Women and Men With Myocardial Infarction.
Raffaele Bugiardini, Beatrice Ricci, Edina Cenko...
https://pubmed.ncbi.nlm.nih.gov/28862963