Actively Recruiting

Age: 18Years +
All Genders
NCT06008392

INTERogating Cancer for Etiology, Prevention and Therapy Navigation

Led by Mayo Clinic · Updated on 2026-04-07

500

Participants Needed

3

Research Sites

516 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is being done to identify markers and causes of cancer by analyzing patient's DNA (i.e., genetic material), RNA, plasma, tissues, or other samples that could be informative for patients with cancer. Cancer genetic testing is a series of tests that finds specific changes in cancer cells and normal cells in the body. Researchers may request to access these data as they explore how to better prevent, screen, or treat cancer. This study is also being done to create a biobank (library) of samples and information to learn more about treating cancer. Discovery of genetic variants in patients with cancer could result in opportunities for cancer prevention, earlier diagnosis or better therapy for cancer.

CONDITIONS

Official Title

INTERogating Cancer for Etiology, Prevention and Therapy Navigation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Has a Mayo Clinic medical record number
  • Confirmed cancer diagnosis
  • Germline and/or somatic tumor/blood testing ordered by clinical provider or delegate
  • Participant aware of cancer diagnosis
  • Able to provide informed consent
  • 18 years old or older
  • Ability to provide blood, saliva, bone marrow aspirate, hair follicle, or archived tissue sample depending on testing group
  • Previous enrollment in specified Mayo Clinic studies with completed genetic testing allowed
Not Eligible

You will not qualify if you...

  • Individuals with situations limiting compliance with study requirements
  • Institutionalized individuals (e.g., Federal Medical Prison)
  • For germline testing only group: prior germline genetic testing with a 100+ multi-gene panel within 1 year of enrollment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Mayo Clinic in Arizona

Scottsdale, Arizona, United States, 85259

Actively Recruiting

2

Mayo Clinic in Florida

Jacksonville, Florida, United States, 32224

Actively Recruiting

3

Mayo Clinic in Rochester

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

C

Clinical Trials Referral Office

CONTACT

K

Katie M. Gano, M.S.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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