Actively Recruiting
Intralesional Injection of Levofloxacin for the Management of Cutaneous Leishmaniasis
Led by Hayder Adnan Fawzi · Updated on 2025-09-30
40
Participants Needed
1
Research Sites
37 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Aim of the study to evaluate the effectiveness of intralesional levofloxacin 0.5% solution as a local injection in treating cutaneous leishmaniasis. In an open-label single-arm clinical trial, all patients were given intralesional levofloxacin injections; the patients had cutaneous leishmaniasis lesions. Each lesion was considered a case in the final analysis. Each lesion will be followed up for 90 days (censor endpoint) or until the lesions are cured. Intralesional levofloxacin (5 mg/ml, 100 ml, Tavanic®, Sanofi, France) will be injected into each lesion based on its size (5 mg/cm2). The infiltration of intralesional dose will be given once weekly for up to 6 weeks. Treatment will be stopped in patients cured before 6 weeks of treatment. A fine insulin needle will be used to infiltrate the lesion.
CONDITIONS
Official Title
Intralesional Injection of Levofloxacin for the Management of Cutaneous Leishmaniasis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with single or multiple (less than seven lesions) lesions of cutaneous leishmaniasis
- Patients aged 20 to 75 years old
You will not qualify if you...
- Patients who received anti-leishmaniasis treatment locally or systemically in the last month
- Patients on prolonged corticosteroid therapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mustansiriyah University
Baghdad, Iraq, 10047
Actively Recruiting
Research Team
H
Hayder Adnan Fawzi, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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