Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT07149207

Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors

Led by Medical University of South Carolina · Updated on 2026-05-12

30

Participants Needed

1

Research Sites

152 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is for adult patients with head and neck cancer who are at risk of recurrence. The purpose of this study is to evaluate whether the use of Indocyanine Green (ICG) dye allows for better identification of tumor tissue during surgical procedures. Participation will include standard of care visits along with administration of ICG dye and imaging during surgery. Participation in this study will last approximately 6 weeks.

CONDITIONS

Official Title

Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult subjects at least 18 years of age.
  • Subjects presenting with squamous cell carcinoma of mucosal origin and are at risk for recurrence.
  • Good operative candidate as determined by the treating physician and/or multidisciplinary team.
  • Subject capable of giving informed consent and participating in the process of consent.
  • Women of childbearing potential must be willing and able to use highly effective contraception from the time of informed consent throughout the study period.
Not Eligible

You will not qualify if you...

  • Pregnant or breastfeeding, or expecting to conceive within the projected duration of the study.
  • Women of childbearing potential with a positive urine or serum pregnancy test at screening unless menopausal or had a hysterectomy.
  • Known allergy to iodides or shellfish.
  • Inadequate organ function at screening including elevated bilirubin or liver enzymes above specified limits.
  • Currently incarcerated individuals.

AI-Screening

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Trial Site Locations

Total: 1 location

1

Medical University of South Carolina Hollings Cancer Center

Charleston, South Carolina, United States, 29425

Actively Recruiting

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Research Team

H

HCC Clinical Trials Office

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Intraoperative Molecular Imaging Using ICG for Head and Neck Tumors | DecenTrialz