Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT06115265

Ketogenic Diet and Diabetes Demonstration Project

Led by University of New Mexico · Updated on 2025-06-25

40

Participants Needed

1

Research Sites

160 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

KDDP is a prospective, 12-month pilot study comparing the effects of a novel lifestyle program, the Ketogenic Diet and Diabetes Demonstration Project (KDDP) to those of the National Diabetes Prevention Program (NDDP). KDDP is modeled to mimic the delivery platform of NDPP with the exception that participants in KDDP will be placed on a medically-supervised ketogenic diet, and participants in NDPP will be placed on a low fat diet. The purpose of this study is to compare the metabolic effects of the KDDP and the NDPP on glycemic control, lipid parameters, blood pressure, heart rate, weight, and coronary artery calcium scores in individuals with either type 2 diabetes or prediabetes.

CONDITIONS

Official Title

Ketogenic Diet and Diabetes Demonstration Project

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Men and women 18 years old or older
  • Body mass index (BMI) of 27 kg/m2 or higher
  • Hemoglobin A1c level of 5.7% or higher and/or fasting plasma glucose between 100 and 125 mg/dL
Not Eligible

You will not qualify if you...

  • History of clinical cardiovascular disease such as stroke, heart attack, or peripheral artery disease
  • LDL cholesterol level of 190 mg/dL or higher
  • Triglyceride level of 500 mg/dL or higher
  • History of type 1 diabetes
  • History of diabetic ketoacidosis
  • Use of insulin treatment
  • Advanced kidney disease
  • Advanced liver disease
  • Terminal cancer
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of New Mexico

Albuquerque, New Mexico, United States, 87131

Actively Recruiting

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Research Team

K

Kristen M Gonzales, MD

CONTACT

M

Matthew Bouchonville, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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