Comparing Ketogenic and Low Fat Diets for Adults with Type 2 Diabetes or Prediabetes and Obesity over 12 Months

What this Trial Is About

Researchers are comparing two lifestyle programs in a 12-month pilot study called the Ketogenic Diet and Diabetes Demonstration Project KDDP. The study evaluates how a medically supervised ketogenic diet compares with the National Diabetes Prevention Programs NDPP low fat diet in people with type 2 diabetes or prediabetes. The main goal is to understand the effects of these diets on blood sugar control, cholesterol, blood pressure, heart rate, weight, and coronary artery calcium scores. Participants are divided into two groups one follows the ketogenic diet with less than 20 grams of carbohydrates daily, while the other follows a low fat diet. Both groups receive the same comprehensive lifestyle counseling and attend weekly educational sessions led by trained dieticians. Participants in the ketogenic group also track their carbohydrate intake daily and perform ketone breath tests regularly to monitor ketosis. Both groups are matched for age, sex, weight, and blood sugar levels. Throughout the study, researchers measure weight, blood pressure, heart rate, hemoglobin A1c, fasting glucose, cholesterol levels, and triglycerides every three months and at the end of the year. Coronary artery calcium scans are done at the start and after 12 months to observe any changes. The study lasts for one year, during which participants receive ongoing support and follow-up to assess the impact of each diet on their health.

Ketogenic Diet and Diabetes Demonstration Project