Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
ID07254013

Left Bundle Branch Area Pacing (LBBAP) Monitoring Assistant: Evaluation of Portable ECG Solution

Led by MicroPort CRM · Updated on 2025-12-05

55

Participants Needed

4

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate the ability to monitor Left Bundle Branch Area Pacing (LBBAP) success criteria using a Smart ECG system during cardiac device implantation. The study focuses on supporting physicians by providing a portable, easy-to-use ECG display and automatic calculation of key ECG indicators such as Left Ventricular Activation Time (LVAT) and V6-V1 interval. This helps doctors concentrate on lead placement with immediate ECG measurements provided by the software. The Smart ECG system consists of a CE-marked Class IIa device, including an ECG monitor, 12-lead ECG cables, ECG viewer software (HookUp Smart V2), and a commercial PC to display and analyze ECG data. The system is used alongside an Electrophysiology ECG monitoring system during pacemaker or cardiac resynchronization therapy (CRT) implantation involving the placement of a pacing lead in the interventricular septum. The study is pre-market and non-pivotal, focusing on device performance and safety based on non-clinical testing. Participants with an indication for LBBAP will undergo the procedure with the Smart ECG system used in addition to the standard EP system. Researchers will assess the capability to monitor LBB success criteria, accuracy of key ECG measurements, identification of LBB transitions, type of LBB capture, signal quality, investigator satisfaction, and safety during the procedure. The study includes baseline and procedure evaluations, with participants followed through the implant process to gather these outcomes.

CONDITIONS

Brief Title

Left Bundle Branch Area Pacing (LBBAP) Monitoring Assistant: Evaluation of Portable ECG Solution

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Subject with indication for LBBAP using an Electrophysiology ECG monitoring system as part of pacemaker or CRT-P or CRT-D implant procedure (de novo implant, device revision or upgrade including LOT-CRT)
  • Subject signed and dated the informed consent form
Not Eligible

You will not qualify if you...

  • Incapacitated subject or under guardianship
  • Inability to understand the purpose of the study
  • Minor subjects
  • Non-menopausal women
  • Patients implanted with other electrically active non-cardiac devices

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - Procedure day

Participants undergo the LBBAP implant procedure using the Smart ECG system as part of their standard care.

1 visit (in-person)

Trial Site Locations

Total: 4 locations

1

CHU de Besançon

Besançon, France, France, 25030

Not Yet Recruiting

2

Clermont Ferrand

Clermont-Ferrand, France, France, 63003

Actively Recruiting

3

CHU Grenoble Alpes

Grenoble, France, France, 38043

Not Yet Recruiting

4

Clinique du Millénaire

Montpellier, France, France, 34000

Actively Recruiting

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Research Team

M

Maria Martino, Project Manager

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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Frequently Asked Questions

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