Observational Registry to Determine Predictors and Outcomes of Patients at Risk of and Diagnosed With Left Ventricular Thrombus

What this Trial Is About

This research aims to better understand left ventricular thrombus (LVT), a blood clot that can form in a weakened heart, especially in people who have had a heart attack or heart failure. About one in six such patients develop these clots, which can lead to serious problems like stroke. The study hopes to gather information on factors linked to clot formation and management to improve care for patients with this condition. Patients included either have a diagnosed LVT with left ventricular dysfunction related to conditions like acute myocardial infarction or cardiomyopathy, or are at risk due to severe heart dysfunction or heart muscle damage. This is an observational study where no treatments are given; instead, participants have routine MRI scans, blood tests, and questionnaires to collect data over time. Participants will provide blood samples at the start and around six months into the study. They will also complete quality of life questionnaires at the beginning and after 12 months. Researchers will record scan results and blood test data and may take additional MRI images during routine scans. The main outcome measured is a composite result assessed from the start to 12 months, with other measures including MRI predictions, blood tests, and quality of life evaluations.

Left Ventricular Thrombus Registry