Diet and Lifestyle Advice to Prevent Colorectal Cancer in Adults Aged 35 to 74 at Higher Risk in France

What this Trial Is About

Researchers are studying how giving advice on diet and lifestyle during colorectal cancer screening affects people at higher risk for colorectal cancer. This study focuses on individuals who have tested positive on a faecal immunochemical test FIT, have adenomas, but do not have colorectal cancer. The goal is to develop and assess a lifestyle intervention based on recommendations from the World Cancer Research Fund and the French National Cancer Institute, aiming to improve adherence to healthy habits and quality of life. The study is a randomized controlled trial with two groups one receiving usual care after screening and colonoscopy, and the other receiving usual care plus evidence-based diet and lifestyle advice. This advice will be delivered by health professionals through various materials like leaflets and digital information. The intervention and baseline measurements occur two to three weeks after colonoscopy. Data will be collected at baseline, 3, 6, and 12 months to measure changes in diet, lifestyle, quality of life, and body measurements. Participants will complete questionnaires about their lifestyle, health, and medical history at several time points. Anthropometric measurements will be taken at baseline and follow-up visits. The main outcome measured is how well participants stick to the recommended lifestyle changes after 3 months. The study will use both statistical and qualitative methods to analyze the results, which could provide valuable information for cancer prevention programs.

Lifestyle Intervention Among Participants of the French Colorectal Cancer Screening Program (LIFE-SCREEN)