Actively Recruiting

Phase Not Applicable
Age: 35Years - 74Years
All Genders
NCT06827366

Lifestyle Intervention Among Participants of the French Colorectal Cancer Screening Program (LIFE-SCREEN)

Led by Centre Leon Berard · Updated on 2026-05-05

800

Participants Needed

1

Research Sites

107 weeks

Total Duration

On this page

Sponsors

C

Centre Leon Berard

Lead Sponsor

I

International Agency for Research on Cancer

Collaborating Sponsor

AI-Summary

What this Trial Is About

The investigators propose a randomized controlled trial to develop and evaluate the impact of promoting advice on diet and lifestyle recommendations for cancer prevention at colorectal cancer screening among individuals who may be at higher risk for colorectal cancer (CRC). The specific objectives of this study are to 1) develop a lifestyle intervention based on evidenced-based diet and lifestyle recommendations (i.e. those proposed by the World Cancer Research Fund (WCRF) and the French National Cancer Institute); 2) evaluate the effect of the intervention on the adherence to the target diet and lifestyle recommendations as well as other subjective health measures, including quality of life; 3) evaluate the effect of the intervention on anthropometrics.

CONDITIONS

Official Title

Lifestyle Intervention Among Participants of the French Colorectal Cancer Screening Program (LIFE-SCREEN)

Who Can Participate

Age: 35Years - 74Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Having read the information note and agreeing to participate
  • Willing and available to commit for a full year
  • At high risk for colorectal cancer but confirmed negative for colorectal cancer
  • Affiliated with a health security system
  • Having a baseline adherence score to the recommendations of 7 or less out of 9
  • Able to read, write, and understand French
Not Eligible

You will not qualify if you...

  • Currently following a strict diet such as meal replacements or diets for conditions like diabetes
  • Immobile due to physical constraints incompatible with physical activity
  • History of extensive intestinal surgery such as colectomy or colon resection
  • Having chronic gastrointestinal illnesses like inflammatory bowel disease, irritable bowel syndrome, or celiac disease
  • Confirmed colorectal cancer or history of any primary cancer
  • Severe malnutrition
  • Pregnant
  • Currently participating in another lifestyle study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Centre Léon Bérard

Lyon, France, France, 69008

Actively Recruiting

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Research Team

I

Inge Huybretchts, PhD

CONTACT

G

Genevieve Nicolas, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Lifestyle Intervention Among Participants of the French Colorectal Cancer Screening Program (LIFE-SCREEN) | DecenTrialz