Actively Recruiting

Age: 18Years +
All Genders
NCT05862792

Liposomal Bupivacaine and Transoral Robotic Surgery

Led by Geisinger Clinic · Updated on 2025-09-09

80

Participants Needed

1

Research Sites

137 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study is for patients with oropharyngeal squamous cell carcinoma. We want to learn more about how we can optimize pain control in patients who undergo transoral robotic surgery (TORS) for oropharyngeal squamous cell carcinoma. Our goal is to determine if a local anesthetic called EXPAREL® (Liposomal Bupivacaine) impacts postsurgical pain and swallow function in patients with oropharyngeal squamous cell carcinoma undergoing TORS. EXPAREL® is an FDA-approved anesthetic drug that provides long-lasting and precise pain relief when injected into the surgical wound. Our study team wants to determine if injecting EXPAREL® into the surgical wound will provide better pain relief and swallow function when compared to patients who do not undergo postoperative EXPAREL® injection. Both options for postoperative pain control are considered standard of care for patients undergoing TORS.

CONDITIONS

Official Title

Liposomal Bupivacaine and Transoral Robotic Surgery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients, 18 years of age or older
  • Patients of all genders
  • Patients undergoing transoral robotic surgery
  • Patients who are able and willing to give consent
Not Eligible

You will not qualify if you...

  • Patients allergic to bupivacaine or other amide anesthetics
  • Patients with a carnitine deficiency

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Geisinger Medical Center

Danville, Pennsylvania, United States, 17821

Actively Recruiting

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Research Team

T

Thorsen Haugen, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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