Actively Recruiting
Analgesic Efficacy of Erector Spinae Block, Quadratus Lumborum Block, and Intrathecal Morphine for Postoperative Pain Relief After Cesarean Section: A Randomized Study
Led by Assiut University · Updated on 2025-04-09
120
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the effectiveness of different nerve blocks and intrathecal morphine for managing pain after cesarean section surgery. The study aims to compare how long these methods provide pain relief after surgery in women aged 18 to 40 years who have elective cesarean deliveries. This randomized trial is sponsored by Assiut University and focuses on postoperative pain control. Participants are assigned to one of three groups: one group receives intrathecal morphine with standard spinal anesthesia; the second group receives the same spinal anesthesia plus a bilateral Quadratus Lumborum nerve block with bupivacaine and dexamethasone; the third group receives spinal anesthesia plus a bilateral Erector Spinae nerve block with the same drugs. All treatments are given during cesarean section surgery. During the study, participants will be monitored to measure how long the pain relief lasts until the first request for additional pain medication within 24 hours after surgery. The trial follows participants through this period to assess and compare the duration of analgesia provided by each method. Safety and pain control will be closely observed throughout the study.
CONDITIONS
Brief Title
Analgesic Efficacy of Different Nerve Blocks in Postoperative Cesarean Section
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 to 40 years old
- At least 37 weeks of pregnancy
- ASA physical status 1 or 2
- Scheduled for elective cesarean delivery
You will not qualify if you...
- Patient refusal to participate
- Unable to cooperate or understand the study
- Presence of local infection
- Bleeding disorders
- Known allergy to any study drug
- ASA physical status higher than 2
- Emergency cesarean operations
- Chronic opioid use within past 3 months
- Neurologic deficit or disorder
- Contraindications to regional anesthesia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Day of cesarean section
Participants receive one of three nerve block procedures or intrathecal morphine during cesarean section for postoperative pain relief.
1 procedure visit (in-person)
Duration - 24 hours post-procedure
Participants are monitored for pain relief duration and any additional analgesic needs after the cesarean section.
1 follow-up visit (in-person)
Trial Site Locations
Total: 1 location
1
Mahmoud Mamdouh Ekram
Asyut, Manfalout, Egypt
Actively Recruiting
Research Team
G
Ghada Abo Elfadl, MD
G
Ghada Abo Elfadl
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here