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Found 3 Actively Recruiting clinical trials
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This research aims to evaluate how the DASH diet and progressive muscle relaxation affect cardiovascular risks in postmenopausal women aged 50 to 60 years who have hypertension. Cardiovascular disease is a leading cause of death, especially among women after menopause, as their blood pressure tends to rise more rapidly. The study focuses on non-drug approaches to managing blood pressure and stress, which are key factors in cardiovascular health. Participants will be assigned to one of three groups one following the DASH diet with antihypertensive medication, another practicing progressive muscle relaxation alongside these medications, and a third group combining both the DASH diet and relaxation techniques with antihypertensive drugs. The DASH diet involves consuming 1600-1800 calories per day of foods low in saturated fat, cholesterol, and sodium, but rich in nutrients like potassium and fiber. Progressive muscle relaxation sessions will be done for 30 minutes, three times a week over three months. During the study, participants will have their blood pressure, cholesterol levels including LDL, HDL, triglycerides, and total cholesterol, and stress levels measured at the start and after three months. Researchers will monitor adherence to the diet and relaxation practices, along with medication use. The goal is to see how these interventions influence cardiovascular risk factors over the three-month period, with careful safety monitoring and follow-up throughout the study.
Actively Recruiting
Researchers are evaluating the effects of nonlinear versus linear periodized resistance training on quality of life in females with hypothyroidism. This condition affects women more often than men and can increase cardiovascular risk factors, especially if undiagnosed. The study focuses on women aged 35 to 45 with controlled hypothyroidism and aims to compare two exercise training plans alongside medical treatment to see how they impact quality of life and related health measures. The study includes three groups of 25 females each one group will receive nonlinear periodized resistance training, another will receive linear periodized resistance training, and the third will continue with medical treatment only. Both exercise programs last 12 weeks, with the nonlinear plan varying workout intensity frequently throughout the week, and the linear plan progressing through set repetitions and loads over the 12 weeks. Medical treatment with levothyroxine will also be given for 12 weeks to all participants. Participants will be involved in training sessions three times per week during the 12-week period. Throughout the study, researchers will assess thyroid hormone levels TSH and Free T4, quality of life using a health questionnaire, triglyceride-glucose index, hand grip strength, and fatigue severity. These measurements will help evaluate how the different exercise plans combined with medical treatment affect physical fitness and quality of life. The entire study runs from January to October 2025, with ongoing monitoring and assessment.
Actively Recruiting
Healthy Volunteer
This research aims to evaluate the clinical and radiographic effects of two types of bone graft materialszinc incorporated bovine derived hydroxyapatite xenograft and bovine hydroxyapatite xenograft aloneused in immediate dental implants. It focuses on addressing the challenge of the residual space between the implant and the socket wall, known as the jumping distance, which can affect implant stability and bone healing. The study explores how zinc incorporation may enhance bone regeneration and implant success compared to standard bovine hydroxyapatite grafts. Participants will receive immediate dental implants combined with either the standard bovine derived hydroxyapatite xenograft or the zinc incorporated version. Both treatments involve surgical implant placement using advanced digital workflows, including computer-aided design and 3D-printed surgical guides to ensure accurate implant positioning. The study groups receive these graft materials immediately after tooth extraction, aiming to evaluate their impact on bone healing and implant integration. During the study, participants will undergo clinical and radiographic assessments over a period of nine months, including measurements of marginal bone loss and bone density using densitometric gray scale values. The research team will monitor implant stability and bone regeneration through imaging and clinical exams. The total participation duration includes treatment and follow-up evaluations to assess the outcomes of each graft material on implant success and bone health.