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Found 4 Actively Recruiting clinical trials

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Actively Recruiting

Healthy Volunteer

Researchers are evaluating the effects of the DASH diet and progressive muscle relaxation on cardiovascular risks in postmenopausal women aged 50 to 60 years. Cardiovascular disease is a leading cause of illness and death, with higher death rates in women than men, particularly postmenopausal women who experience faster increases in blood pressure. This study focuses on non-drug approaches to manage stress and lower blood pressure to reduce cardiovascular risks in this group. Participants will follow the DASH diet, consuming 1600 to 1800 calories per day, which emphasizes low saturated fat, cholesterol, and sodium intake while encouraging foods rich in potassium, calcium, magnesium, fiber, and protein. Alongside the diet, some participants will practice progressive muscle relaxation for 30 minutes, three times a week, over three months. All groups will continue their prescribed antihypertensive medications during the study. During the study, researchers will monitor blood pressure and blood lipid levels, including systolic and diastolic blood pressure, LDL cholesterol, HDL cholesterol, triglycerides, and total cholesterol over three months. Participants will undergo assessments to track these cardiovascular risk markers while continuing their treatments, helping to determine the impact of the diet and relaxation techniques on heart health in postmenopausal women.

Age: 50Years - 60YearsFEMALEPhase Not Applicable
1 location
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Actively Recruiting

Researchers are evaluating the effects of nonlinear versus linear periodized resistance training on the quality of life in females with hypothyroidism. Hypothyroidism is a common endocrine disorder affecting mainly women between 35 and 45 years old, with potential cardiovascular risks if untreated. Exercise may improve quality of life by enhancing physical fitness and reducing symptoms, and this study aims to compare two different resistance training methods. Participants will undergo either a nonlinear or linear periodized resistance training program for 12 weeks, alongside medical treatment. The nonlinear training involves three weekly sessions with varying intensities ranging from very light to very heavy, changing frequently from session to session. The linear training program follows a systematic progression of sets and repetitions over 12 weeks with increasing loads, adjusted individually under supervision. Medical treatment will also be provided during this period. Throughout the study, participants will be assessed at 12 weeks for serum thyroid stimulating hormone (TSH) and Free T4 levels, as well as health-related quality of life through questionnaires. Researchers will monitor adherence and collect data on physical and biochemical outcomes to evaluate the impact of these training programs on hypothyroid women. The total participation duration is 12 weeks, with evaluations at the study's end.

Age: 35Years - 45YearsFEMALEPhase Not Applicable
1 location
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Actively Recruiting

Researchers are evaluating the effects of popliteus muscle release compared to Kinesio taping on pain intensity, function, dynamic balance, and quadriceps muscle strength in patients with patellofemoral pain syndrome. This condition is a common and challenging disorder characterized by diffuse pain around the front and inner side of the knee, especially affecting runners and limiting daily activities involving knee flexion. The study aims to better understand treatment options due to the unclear causes and controversial management of this syndrome. Participants will receive either myofascial release targeting the popliteus muscle or Kinesio taping applied to the same muscle, alongside traditional physical therapy treatments including quadriceps, hip abduction, and hip extension strengthening, hamstring stretching, and gait training. These interventions will be assessed to determine their impact on symptoms and function. Participants will have their pain intensity, knee function, and balance measured at the start of the study and again after 4 weeks of treatment. The study involves monitoring these outcomes to observe changes over time and assess the effectiveness of the treatments. The total participation age range is 18 to 30 years old, focusing on those with a minimum 3-month history of patellofemoral pain.

Age: 18Years - 30YearsAll GendersPhase Not Applicable
1 location
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Actively Recruiting

Healthy Volunteer

This research investigates the clinical and X-ray effects of two types of bone graft materials used during immediate dental implant placement: zinc-incorporated bovine derived hydroxyapatite xenograft and bovine hydroxyapatite xenograft alone. The study aims to address the challenge of bone defects caused by gaps between the implant and the tooth socket, which can affect implant stability. It explores how zinc, known for promoting bone growth and reducing bacteria, might enhance the performance of hydroxyapatite in bone healing around implants. Participants will receive immediate dental implants with either the zinc-enriched xenograft or the standard bovine hydroxyapatite xenograft. These materials serve as scaffolds to support new bone growth and improve implant integration. The study involves precise implant placement using digital design and 3D-printed surgical guides to ensure accurate positioning and restoration. Both groups will be monitored to compare clinical outcomes. Throughout the study, participants will undergo clinical checks and radiographic evaluations to assess bone changes around the implant, focusing on bone loss over nine months. Researchers will track implant stability, bone healing, and any complications. The study includes adults aged 21 to 50 who need implants in the lower jaw, and participants will be followed to observe the safety and effectiveness of the two graft materials over time.

Age: 21Years - 50YearsAll GendersPhase Not Applicable
1 location
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