Comparing Nonlinear and Linear Resistance Training on Quality of Life in Women Aged 35 to 45 With Hypothyroidism

What this Trial Is About

Researchers are evaluating the effects of nonlinear versus linear periodized resistance training on quality of life in females with hypothyroidism. This condition affects women more often than men and can increase cardiovascular risk factors, especially if undiagnosed. The study focuses on women aged 35 to 45 with controlled hypothyroidism and aims to compare two exercise training plans alongside medical treatment to see how they impact quality of life and related health measures. The study includes three groups of 25 females each one group will receive nonlinear periodized resistance training, another will receive linear periodized resistance training, and the third will continue with medical treatment only. Both exercise programs last 12 weeks, with the nonlinear plan varying workout intensity frequently throughout the week, and the linear plan progressing through set repetitions and loads over the 12 weeks. Medical treatment with levothyroxine will also be given for 12 weeks to all participants. Participants will be involved in training sessions three times per week during the 12-week period. Throughout the study, researchers will assess thyroid hormone levels TSH and Free T4, quality of life using a health questionnaire, triglyceride-glucose index, hand grip strength, and fatigue severity. These measurements will help evaluate how the different exercise plans combined with medical treatment affect physical fitness and quality of life. The entire study runs from January to October 2025, with ongoing monitoring and assessment.

Periodization Resistance Training on Quality of Life in Females With Hypothyroidism