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Researchers are evaluating the impact of the SAM Ergonom light (SAM) device on helping individuals who cannot transfer independently from lying down to sitting at the edge of a bed. This randomized, open-label, cross-over study compares the SAM device with an over bed pole hoist (raising arm) to see which better supports transfer independence in patients using medical beds. Participants are adults unable to transfer independently and currently in medical or rehabilitation care. Participants will use both devices in a randomized order: one group uses the SAM device for 7 days followed by the control device for 7 days, while the other group uses the control device first and then the SAM device. The SAM device is a removable frame fixed to the bed with a handle to assist sitting up, and the control device is a standard over bed pole hoist. This cross-over design allows each participant to try both devices during the study. During the study, therapists will observe and measure participants' transfer independence using the Functional Independence Measure (FIM) bed transfer item at days 7 and 14. Participants are monitored directly by therapists to assess how well they can transfer from lying to sitting. The study also collects safety and usability data during and after device use. Total participation includes 14 days of device use under clinical supervision.

Researchers are investigating how patients with chronic lateral epicondylalgia, also known as tennis elbow, respond to platelet-rich plasma (PRP) injections. This study aims to identify which patients benefit from PRP treatment and to explore factors such as clinical, demographic, and occupational characteristics that may influence treatment response. The goal is to understand the number of patients who show improvement 90 days after PRP injection and to develop a model that can predict who is more likely to respond. The study includes adults aged 18 and older who have chronic lateral elbow pain lasting more than three months and who have received a PRP injection within the last 48 hours. Participants will attend three visits: at the start of the study (Day 0), Day 45, and Day 90. During these visits, clinical exams, pain assessments, functional tests like hand grip strength, and questionnaires will be conducted. The Clinical Global Impression - Change (CGI-C) scale will be used at Day 45 and Day 90 to evaluate treatment response. Participants will provide information about their professional activities, medical history, and any treatments received. The study procedures mostly align with routine care except for the added CGI-C scale assessments. The researchers will monitor changes in pain, hand strength, and function over three months, aiming to compare outcomes between those who respond to PRP and those who do not. The study is conducted in France at two medical centers, and each participant will be followed for about 90 days.

Researchers are evaluating the AutonHomeae self-education device for rehabilitation in patients who have experienced a stroke, specifically hemorrhagic unilateral cortico-subcortical hemispheric stroke or ischemic stroke. This study aims to address issues related to therapy interruptions by combining self-education and telecare to maintain therapeutic connection without requiring patient travel. Previously, the device showed usefulness and safety in a feasibility study with hemiplegic patients. The trial includes two groups: an experimental group using the AutonHomeae device for self-rehabilitation and tele-rehabilitation alongside conventional rehabilitation, and a control group receiving only conventional in-centre rehabilitation. Forty participants will be randomized equally between groups across four centers. The study is designed as a pilot to assess the impact of this combined care pathway on sensory-motor recovery and factors like length of hospital stay and functional and economic outcomes. Participants will be monitored over 15 weeks with assessments at the start and at 6 weeks to evaluate sensory-motor recovery. The study collects data on the evolution of recovery using the technical platform and home-based interventions. The goal is to determine if the experimental care is at least as effective as the control in improving recovery after stroke, while maintaining safety and patient engagement throughout the study duration.

Researchers are evaluating the use of compression garments as an alternative treatment for pain in people with Complex Regional Pain Syndrome (CRPS) affecting the upper limbs. CRPS often involves neuropathic pain and sometimes swelling (edema), which compression garments like gloves or sleeves are sometimes used to reduce. This study aims to assess whether wearing these garments can notably reduce neuropathic pain in affected patients. The trial is not classified by phase and focuses on patients with CRPS diagnosed by specific clinical criteria.

Researchers are evaluating the impact of upper limb (UL) assistance devices on users, focusing on both clinical and psychosocial aspects. This study is part of a larger project called PI3 ASSISTMOV, which aims to develop advanced robotic exoskeletons to support movement for people with disabilities. The study explores how these devices affect independence in daily activities, satisfaction, quality of life, social participation, and social perceptions, while also considering economic factors. Participants in this study are regular users of UL movement assistance devices, such as grasping gloves, mealtime aids, robotic manipulation arms, and arm supports, all of which have CE marking confirming compliance with European regulations. No devices are provided by the study; instead, participants share their experiences using their own devices integrated into their daily lives. Data is collected through interviews and questionnaires to understand the benefits, limitations, and factors influencing the adoption of these technologies. During the study, researchers gather information on users' experiences through questionnaires and interviews, assessing the psychosocial impact using tools like the French-Quebec version of the Psychosocial Impact of Assistive Devices Scale. Participants must have been using their UL device for at least two months and have access to a computer with internet for videoconferencing. The study also collects information on the care pathway from prescription to daily use and monitors the overall satisfaction and social participation of users, aiming to improve future device recommendations and developments.

This research focuses on adults aged 18 to 60 who have experienced the rare and serious condition of double amputation of both forearms. It evaluates and compares two treatment strategies: bilateral allograft (transplant) of the hands and forearms versus the use of prosthetic forehands. The aim is to assess these options in terms of costs, quality of life, usefulness, satisfaction, autonomy, and social integration, building on previous findings that hand transplants can restore autonomy but require immunosuppressive treatment. Participants may receive either a bilateral allograft of the hands and forearms or prosthetic forehands. The transplant group must meet specific health criteria, such as having had their amputation at least three months prior and no severe psychiatric or uncontrolled medical conditions. The study compares the two approaches, considering both medical and economic outcomes over time. During the study, researchers will monitor costs and other important outcomes over 36 months. They will assess autonomy, quality of life, and social integration, along with medical complications related to treatments. The study builds on earlier results showing that hand transplants can help patients regain function and return to work, despite the need for ongoing immunosuppression and possible risks. This evaluation will help guide treatment choices for patients with bilateral upper limb amputations.

Patients who have experienced a stroke (cerebrovascular accident) may have difficulty accurately judging their own cognitive and driving abilities. This research evaluates whether video feedback during a driving assessment can improve patients' awareness of their driving skills compared to standard recommendations without video feedback. The study aims to support multidisciplinary teams in making informed decisions about patients resuming driving after a stroke. The study involves two groups of post-stroke patients. One group of 35 patients will review and analyze four driving situations using video feedback after a driving session. The other group of 35 patients will discuss the same driving situations without video feedback, following usual recommendations. Researchers will compare responses from questionnaires and interviews given before and after the driving sessions to assess the effect of video feedback. Participants will undergo a driving situation assessment and complete self-assessment questionnaires. Researchers will measure participants' awareness of their driving behavior on the day of the assessment. The study includes patients between 18 and 85 years old who have had a stroke within the past 1 to 6 months, hold a driving license for more than 3 years, and have not resumed driving. Safety and cognitive stability are monitored through medical evaluations and consent procedures throughout the study.

Cerebral palsy is a leading cause of disability in children, with nearly 40% experiencing sleep disorders that are often not routinely checked. These sleep problems can affect a child's brain function, physical health, and environment, making proper diagnosis and treatment important. However, the standard test for sleep disorders, polysomnography (PSG), is not widely accessible, limiting timely diagnosis for many children with cerebral palsy. This research studies the use of connected tools to improve screening for sleep disorders in children with cerebral palsy aged 6 to 15 years. Parents will record their child's sleep at home for one night using these connected technologies. After this, the child will spend a night in the hospital where sleep will be recorded simultaneously by PSG and the connected tools to compare their results. Participants will be monitored for 15 days to assess how well the connected tools detect sleep disorders by measuring sensitivity and specificity. The study aims to select children who need PSG and tailored management based on the connected tools' screening. This approach hopes to enable earlier diagnosis and better care for sleep disorders in children with cerebral palsy.