Saint Sebastien De Morsent

Stroke is a common and serious condition, affecting many individuals each year and often leading to cognitive impairments such as hemineglect. Hemineglect causes difficulty responding to stimuli on one side, typically after a right hemisphere stroke, and often persists long-term, impacting daily function and rehabilitation outcomes. This research explores the use of immersive virtual reality combined with multisensory stimulation to reduce the functional effects of hemineglect in adults who have experienced a right-sided stroke within the past three months. The study involves a pilot design with repeated evaluation and rehabilitation sessions conducted in a hospital setting. Participants will undergo weekly assessments for 10 to 12 weeks using the Catherine Bergego Scale to measure how hemineglect affects autonomy. After an initial evaluation phase lasting 3 to 5 weeks, patients will receive three weekly 45-minute rehabilitation sessions over five weeks, including a 15-minute immersive virtual reality experience using the VirtySensae multisensory travel capsule. This capsule stimulates four senses simultaneously through visual, auditory, olfactory, and tactile inputs. During the study, participants will attend weekly evaluation sessions led by occupational therapists who will assess the impact of hemineglect and monitor tolerance to virtual reality. Rehabilitation sessions include review and explanation components, with a focus on patient comfort and response to the virtual reality treatment. The study aims to measure changes in autonomy, awareness of hemineglect, and the ability to tolerate the immersive environment over the 12-week period.

Researchers are evaluating the impact of equine-assisted therapy on the quality of life of children aged 8 to 12 years with Autism Spectrum Disorder ASD and their families. This interventional, prospective, and monocentric pilot study aims to assess the feasibility of a larger, more rigorous trial. It focuses on measuring changes in quality of life using the PedsQL1 4.0 questionnaire for children and parents and the PAR-DD-QOL questionnaire for parents, along with a qualitative analysis of childrens progress in communication, motor skills, and social connections. Participants will receive 15 equine therapy sessions, conducted twice a week over 7 to 8 weeks. Each 60-minute session includes activities such as emotional expression, grooming, contact with the horse, exercises on foot or horseback, and debriefing. The study begins with participant selection, consent, and explanation, followed by the therapy sessions conducted at the equine therapy center of La Musse Hospital. Throughout the study, quality of life is assessed five times using questionnaires completed by children and parents before and after selected therapy sessions. Equine therapists will also complete tracking sheets to monitor childrens behavioral progress. Researchers will analyze these scores and progress reports to understand the therapys effects. Participants can withdraw at any time, and strategies like reminders and scheduling aim to support adherence to the therapy program.

Parkinsons disease is a common neurodegenerative disorder characterized by difficulties with movement and swallowing, known as dysphagia, which affects many patients at various stages. This condition can severely impact quality of life and lead to serious complications like aspiration pneumonia. Researchers are investigating the relationship between gait freezing, a common movement difficulty, and oropharyngeal freezing, a swallowing-related issue, to better understand their connection and improve early detection and care. Participants will undergo several assessments during their OFF medication phase, including the Unified Parkinsons Disease Rating Scale UPDRS, Timed Up & Go TUG test, New Freezing of Gait Questionnaire NFOG-Q, BAASTA Battery, and a clinical swallowing evaluation. Based on the results of gait freezing assessments, participants will be grouped into those with or without freezing of gait. If swallowing problems are suspected during evaluation, a swallowing radiographic study called pharyngography will be performed to clarify the nature of the disorder. Throughout the study, participants will be assessed for the presence of oropharyngeal freezing using pharyngography and clinical tests. Researchers will measure symptom severity, fluctuations, gait freezing, rhythm abilities, swallowing function, aspiration severity, food ingestion effectiveness, and quality of life impacts. All assessments occur at enrollment during the OFF phase. The study aims to better understand these freezing phenomena and their effects on swallowing and daily living in Parkinsons patients.

Chronic obstructive pulmonary disease COPD is a serious lung condition that reduces exercise tolerance and quality of life. Pulmonary rehabilitation helps improve breathing, exercise capacity, and overall well-being, but many patients face barriers such as travel difficulties and limited rehab center availability. This research compares a home-based telerehabilitation program to traditional center-based pulmonary rehabilitation to assess their effects on exercise endurance in adults with COPD. The study randomly assigns participants aged 45 to 80 with stable COPD to either a home-based or center-based rehabilitation group. Both groups complete 24 sessions over eight weeks, including endurance training on a cycle ergometer, muscle strengthening, balance exercises, and therapeutic education tailored to individual needs. The home-based group uses equipment like a cycle ergometer, pulse oximeter, activity tracker, and a tablet app for guidance and remote monitoring, while the center-based group attends sessions at rehabilitation centers. Both groups have initial and final in-person assessments. Participants will undergo assessments before and after the program, including exercise endurance tests on a cycle ergometer. Researchers will monitor adherence, physical activity, quality of life, cognitive function, and health events over one year. Regular support and education aim to ensure safety and effectiveness. The total involvement includes rehabilitation sessions, assessments, and follow-up evaluations, with safety measures in place to minimize exercise-related risks.

Researchers are evaluating the effect of rhythmic auditory cueing on the frequency of rolling, an involuntary tongue movement during swallowing, in patients with idiopathic Parkinsons disease who have swallowing difficulties. The study aims to see if introducing rhythmic sounds during rehabilitation can reduce rolling frequency and improve swallowing function, physical health, and quality of life. This pilot study focuses on patients with dysphagia related to Parkinsons disease and investigates the potential benefits of auditory rhythm in therapy. Participants will take part in swallowing rehabilitation sessions three times a week for seven weeks under the guidance of a speech therapist. During each session, they will swallow saliva and specially textured foods timed to a metronome rhythm, with the goal of matching the rhythm of healthy swallowing. The study includes three full assessments involving swallowing examinations and pharyngography conducted before starting the therapy, immediately after the 7-week program, and three months later. Throughout the study, participants will undergo clinical speech therapy evaluations and radiographic swallowing tests to measure the frequency of rolling and swallowing abilities at three time points before treatment, after treatment, and at a 3-month follow-up. Researchers will monitor changes in swallowing function and quality of life, with all sessions and assessments occurring at the hospital. The total participation spans several months, including the rehabilitation period and follow-up evaluation.