Actively Recruiting
Study of the Link Between Freezing of Gait and Oropharyngeal Freezing in Parkinson's Patients
Led by Hopital La Musse · Updated on 2024-12-04
66
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Parkinson's disease is a common neurodegenerative disorder characterized by difficulties with movement and swallowing, known as dysphagia, which affects many patients at various stages. This condition can severely impact quality of life and lead to serious complications like aspiration pneumonia. Researchers are investigating the relationship between gait freezing, a common movement difficulty, and oropharyngeal freezing, a swallowing-related issue, to better understand their connection and improve early detection and care. Participants will undergo several assessments during their OFF medication phase, including the Unified Parkinson's Disease Rating Scale (UPDRS), Timed Up & Go (TUG) test, New Freezing of Gait Questionnaire (NFOG-Q), BAASTA Battery, and a clinical swallowing evaluation. Based on the results of gait freezing assessments, participants will be grouped into those with or without freezing of gait. If swallowing problems are suspected during evaluation, a swallowing radiographic study called pharyngography will be performed to clarify the nature of the disorder. Throughout the study, participants will be assessed for the presence of oropharyngeal freezing using pharyngography and clinical tests. Researchers will measure symptom severity, fluctuations, gait freezing, rhythm abilities, swallowing function, aspiration severity, food ingestion effectiveness, and quality of life impacts. All assessments occur at enrollment during the OFF phase. The study aims to better understand these freezing phenomena and their effects on swallowing and daily living in Parkinson's patients.
CONDITIONS
Brief Title
Study of the Link Between Freezing of Gait and Oropharyngeal Freezing in Parkinson's Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of idiopathic Parkinson's disease established by a neurologist
- Patient affiliated with the social security system
- Patient aged over 18 years
You will not qualify if you...
- Patients under legal protection measures
- Neurological history that could be the cause of a swallowing disorder (e.g., stroke) or a history of ENT cancer
- Patient with a gastrostomy without oral intake
- Pregnant women or those suspected of being pregnant
- Minor patients
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - At enrollment
Participants undergo a series of assessments including the Unified Parkinson's Disease Rating Scale (UPDRS), Timed Up & Go (TUG) Test, New Freezing of Gait Questionnaire (NFOG-Q), BAASTA Battery, and a clinical swallowing assessment during their OFF phase to evaluate freezing of gait and swallowing function.
1 visit (in-person)
Duration - Ongoing after enrollment
Participants are observed to assess the severity, fluctuation, progression of clinical symptoms, and the impact on daily life. Those with signs of swallowing disorders may be referred for pharyngography to further specify the nature of these disorders.
Visit frequency not specified
Trial Site Locations
Total: 1 location
1
Hôpital La Musse
Saint-Sébastien-de-Morsent, France, 27180
Actively Recruiting
Research Team
H
Héloïse BAILLET, PhD
J
Julie LE BALC'H
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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