Lido

Researchers are investigating the brain activity related to Mild Cognitive Impairment (MCI) in people with Parkinson's disease (PD). The study aims to find connections between difficulties in thinking and movement and brain signals seen in MCI among PD patients. The study includes 42 participants divided into three groups: healthy individuals, PD patients with MCI, and PD patients without MCI. Each participant will undergo detailed cognitive testing and brain activity recording using high-density electroencephalography (hdEEG) during rest and while performing cognitive tasks. Structural magnetic resonance imaging (MRI) will also be used to provide detailed brain images to help understand brain network connectivity.

Financial Abilities (FA) refer to the skills needed to manage money and financial matters independently, aligned with one's values and interests. This research evaluates FA in people with neurological conditions such as Mild Cognitive Impairment, Parkinson's disease, and Stroke. It aims to understand how cognitive functions, especially executive functions, and brain structures relate to financial skills. The study also focuses on developing and testing a telerehabilitation program called FINAGE to improve FA remotely. Participants will be assigned to one of two groups: the telerehabilitation group or the conventional treatment group. Both groups will receive their respective interventions for one hour a day, five days a week, over four weeks. The study includes assessments before and after the interventions to examine changes in financial abilities, cognitive functions, and brain connectivity. During the study, participants will undergo evaluations using the NADL-F battery for financial skills, cognitive assessments, and neuroimaging tests. Researchers will measure changes at the start and after four weeks of treatment to observe improvements and brain reorganization. The study also monitors the safety and effectiveness of the remote rehabilitation program. Total participation includes initial assessment, four weeks of treatment, and follow-up evaluations.

Researchers are evaluating visuospatial skills and psychological effects in patients with Multiple Sclerosis (MS) and those who have had West Nile virus infection (vWN). Both conditions can impair cognitive functions such as attention, memory, executive functions, and motor skills. This study focuses on understanding these cognitive and psychological impacts, especially visuospatial abilities, which help people navigate and interact with their environment. The research also aims to test a new rehabilitation tool for improving these functions, as current knowledge on visuospatial deficits, particularly in vWN patients, is limited and inconsistent. Participants will receive 10 sessions of cognitive training using Mindlenses Professional, a device that combines prismatic lens adaptation with digital serious games on a tablet to target visuospatial and other cognitive functions like attention and executive skills. This intervention will be compared with conventional rehabilitation involving computerized exercises focusing on key cognitive areas. The prismatic adaptation is thought to enhance brain activity in areas related to visuospatial processing and cognitive control. During the study, patients will have neuropsychological and psychological evaluations before and after the treatment to measure changes in cognitive performance. The main outcome is assessing cognitive improvements two weeks post-intervention. Researchers will monitor psychological status and visuospatial abilities through standardized tests and questionnaires. Participants' vision and hand use will be preserved during assessments, and safety and consent procedures will be followed throughout the study.