Lido

Researchers are investigating the brain activity linked to Mild Cognitive Impairment MCI in people with Parkinsons disease PD. The study aims to find connections between difficulties in thinking and movement and brain signals measured by electroencephalography EEG. It involves 42 participants divided into three groups healthy people, those with PD and MCI, and those with PD but no MCI. The study uses brain scans and cognitive tests to understand these changes better. Participants will undergo detailed neuropsychological testing to classify their cognitive status. They will have high-density EEG recordings both while resting and performing cognitive tasks to measure brain activity. Structural magnetic resonance imaging MRI will also be done to combine brain structure data with EEG results, helping to map brain connectivity accurately. During the study, participants will complete cognitive evaluations, frailty assessments, and accuracy tests during tasks. Researchers will analyze brain wave patterns and functional connections in the brain from the EEG and MRI data. The study focuses on how brain connectivity relates to cognitive and motor impairments, aiming to improve future treatments and prevention. The research is observational and includes follow-up at baseline for all measures.

Financial Abilities FA refer to the skills needed to manage money and financial matters independently, aligning with personal values and interests. This research focuses on assessing FA in people with neurological conditions such as Mild Cognitive Impairment, Parkinsons disease, and Stroke. It also explores the cognitive and brain-related factors behind these abilities and aims to develop a telerehabilitation tool to improve financial independence in these groups. Participants are assigned to one of two groups a telerehabilitation group using the FINAGE tablet to perform cognitive training tasks related to financial abilities and underlying cognitive functions, or a conventional treatment group receiving standard cognitive training. Both interventions last for 1 hour per day, 5 days a week, for 4 weeks. The telerehabilitation program includes various modules targeting specific cognitive domains like attention, memory, language, and executive functions. During the study, participants undergo assessments of their financial abilities, cognitive performance, and brain connectivity before and after the 4-week treatment period. Researchers will use neuroimaging and cognitive tests to measure changes and understand how rehabilitation affects the brain and behavior. The study helps evaluate how well the telerehabilitation program supports financial skills and brain function over this timeframe.

Researchers are studying visuospatial abilities and psychological outcomes in patients with Multiple Sclerosis MS and West Nile virus infection vWN. Both conditions can affect cognitive functions such as attention, memory, and executive skills. This study aims to better understand these impairments and test a new rehabilitation approach to improve visuospatial and cognitive functions. Participants will receive 10 sessions over 2 weeks of cognitive training using Mindlenses Professional, a device that combines prismatic adaptation therapy with digital serious games targeting attention, executive functions, and language. There is also a comparison group receiving standard computerized cognitive rehabilitation offered by the hospital. During the study, patients will undergo neuropsychological and psychological evaluations before and after the treatment to assess changes in cognitive performance and psychological status. The primary outcome measures cognitive changes after the 2-week intervention, while secondary outcomes assess psychological effects. The study involves randomized assignment and single masking, with a total participation period of about 2 weeks.