Seri Kembangan

Researchers are studying the effects of four different relaxation techniques on the physical and mental well-being of mothers who are breastfeeding preterm infants. This study focuses on mothers of premature babies born between 28 and 35 weeks gestation, aiming to see how each intervention influences heart rate, blood pressure, fingertip temperature, breast milk cortisol levels, and feelings of relaxation. The goal is to identify which relaxation method works best for this group. The study involves five sessions per participant, each testing a different approach Guided Imagery Meditation, Religious Recitation, Infant Video with Music, Distraction with News and Media, and a Control session with minimal activity. Each session lasts about 10 to 14 minutes and is spaced 1 to 2 days apart. Participants will experience all five interventions in a randomized order to compare effects within the same mothers. During the study, mothers will have their heart rate, blood pressure, fingertip temperature, and breast milk cortisol measured before and after each session. They will also report their perceived relaxation levels. The study will last about two weeks from enrollment through the completion of all five sessions. Additional measures include breast milk fat, carbohydrate, and total energy content. This research is led by Universiti Putra Malaysia and focuses on Muslim mothers who are non-smokers and currently breastfeeding.

Diabetes is a growing health concern worldwide, especially in Saudi Arabia where it affects a significant portion of the population. This research aims to evaluate the effects of date seed extract on blood sugar control and cardiovascular risk in adults with Type 2 diabetes. The study is designed as a randomized controlled trial to fill the gap in data on how date seed consumption might influence diabetes management and heart health. Participants will be divided into two groups one group will take capsules containing date seed powder, consuming 5 grams twice daily after meals for three months, while the control group will not receive any capsules. The date seed powder is prepared by washing, drying, grinding the seeds, and filling gelatin capsules. Participants will be monitored regularly, including assessments at the start, after one month, and at two months following the intervention. Adherence will be supported through twice-weekly contact and a checklist. During the study, participants will provide information through a questionnaire covering lifestyle, demographics, and clinical factors. Physical measurements such as blood pressure, body mass index, and biochemical tests will be collected. Researchers will measure changes in blood glucose, cholesterol, blood pressure, physical activity, daytime sleepiness, and dietary intake over 12 weeks. The study will also track participant adherence and safety, with data analyzed to understand the impact of date seed extract on diabetes and cardiovascular risk.

This research aims to develop, implement, and assess an educational program to improve dietitians knowledge, attitudes, and practices related to renal nutrition for chronic kidney disease CKD patients in public hospitals in Saudi Arabia. The study hypothesizes that dietitians who participate in the program will show significant improvements compared to those who do not. The findings are intended to help dietitians provide better nutritional care to CKD patients. The study is a cluster randomized controlled trial involving 100 dietitians divided into two groups an intervention group and a control group. The intervention group will take part in a five-week educational program covering five lessons on nutrition assessment, malnutrition, nutrient deficiencies, nutrition intervention, and counseling skills tailored for CKD. This program will be delivered online via Zoom using lectures, workshops, brainstorming, case studies, and various learning materials. The control group will not receive any intervention. Participants will be evaluated through interviews at three points before the program starts baseline, one week after the program ends, and three months later. Researchers will assess dietitians competencies in knowledge, attitude, and practice regarding renal nutrition using questionnaires. Data will be analyzed with statistical software to measure changes over time. The entire process aims to monitor improvements and long-term retention of the educational content.

Dental caries is a major public health problem worldwide, especially affecting childrens health, development, and well-being. This study evaluates a school-based oral health education program in Al Lith City, Saudi Arabia, targeting boys aged 10 to 11 years. The goal is to improve knowledge, attitudes, and behaviors related to oral hygiene and eating habits through a cluster randomized controlled trial involving four primary schools. The research aims to address gaps in oral health knowledge and practices that impact childrens overall health. The intervention consists of interactive classroom sessions led by a dental care professional over one school month. The first session focuses on building knowledge and positive attitudes about oral health, while the second session teaches behavioral skills to improve oral hygiene and eating habits. Participants receive take-home educational materials. Effectiveness is measured by comparing questionnaire results before, immediately after, and six months following the program. Participants complete questionnaires assessing their oral health knowledge, attitudes, and practices at three time points baseline, 8 weeks post-intervention, and 16 weeks post-intervention. Additional measures include self-efficacy and social support. Researchers analyze data using statistical methods to determine the programs impact. The study runs from March 2024 to August 2027 and includes safety monitoring of participants health and attendance throughout the intervention period.

This research aims to observe and evaluate clinical differences in patients with migraine who receive preventive treatment targeting calcitonin gene-related peptide CGRP or its receptor. The study focuses on monoclonal antibodies erenumab, galcanezumab, fremanezumab, eptinezumab and gepants rimegepant, atogepant over a 2-year observation period. It includes patients who meet local reimbursement criteria and have a confirmed migraine diagnosis following international standards. Participants will start treatment with one of the anti-CGRP monoclonal antibodies or gepants as prescribed. Baseline assessments will be done before treatment begins. Follow-up visits will occur every 6 months to check treatment effectiveness, side effects, patient-reported outcome measures, and eligibility to continue using the study drug. The observation phase will last for 2 years. During the study, participants will undergo regular evaluations including headache frequency, migraine impact, anxiety, depression, sleep quality, and quality of life measures through various questionnaires. Researchers will monitor changes in monthly headache and migraine days, along with other clinical and patient-reported outcomes. The study will ensure ongoing safety and treatment monitoring throughout the 2-year period.

Researchers are investigating whether biscuits made with mature okra flour can help young adults feel fuller and affect certain blood markers compared to standard biscuits. Mature okra, often discarded due to its tough texture, is dried and ground into flour that replaces 10% of wheat flour in a specially made biscuit. This study aims to assess the impact of these okra-incorporated biscuits on feelings of fullness and metabolic responses in healthy young adults. Participants will take part in a single-blind, randomized trial where they consume either the biscuit with 10% mature okra flour or a control biscuit made entirely of wheat flour on separate occasions. The study measures perceived fullness using the Satiety Labeled Intensity Magnitude SLIM scale over 165 minutes after eating, alongside blood glucose and hormone levels related to appetite. Blood samples collected at specific times will be analyzed for insulin, GLP-1, PYY3-36, CCK, ghrelin, and metabolite profiles. During the study, participants will undergo satiety assessments and blood draws at baseline and multiple time points up to 165 minutes after biscuit consumption. Researchers will evaluate changes in appetite sensations and metabolic markers using specialized lab tests. The study also includes measuring energy intake at a later meal to understand appetite regulation. The entire participation involves consuming biscuits under controlled conditions and attending scheduled follow-up assessments to monitor responses.

Researchers are evaluating an ergonomics intervention program aimed at reducing work-related musculoskeletal disorders MSDs among dental healthcare workers in Dubai government hospitals. These disorders, affecting up to 90% of dental professionals, mainly impact the lower back, neck, shoulders, and upper extremities due to repetitive tasks and static postures. This study uses a cluster randomized controlled trial involving three hospitals with 110 participants to assess the interventions effect on MSD prevalence, severity, mental health, physical activity, and knowledge, attitudes, and practices KAP related to MSDs. The intervention group will participate in an educational program based on Social Cognitive Theory, including six weekly sessions covering topics such as MSD causes, ergonomic principles, equipment positioning, symptom recognition, rest breaks, and physical activity. This program involves booklets, lectures, workshops, demonstrations, practical exercises, and stretching routines. The control group will not receive any educational intervention. Data will be collected at baseline, one month post-intervention, and three months follow-up to evaluate changes. Participants will be assessed through measures of MSD prevalence and severity, mental health, physical activity, and KAP scores at three time points. Statistical analyses will examine differences within and between groups over time. The study will monitor adherence to the intervention and collect data to identify predictors of MSDs among dental workers. The total participation includes baseline assessment, intervention period, and follow-up evaluations extending to three months after the intervention.

Metabolic syndrome MetS is a widespread health condition marked by a group of risk factors including abdominal obesity, high blood pressure, elevated blood sugar, high triglycerides, and low HDL cholesterol. These factors increase the chances of developing heart disease, type 2 diabetes, and early death. In Saudi Arabia, MetS affects a significant portion of adults, especially men and those living in certain regions, with causes tied to obesity, inactivity, smoking, and poor diet. Despite evidence supporting interventions like weight loss, intermittent fasting, and exercise, no randomized controlled trials have studied their combined effect on MetS in Saudi adults. This research will test how well modified intermittent fasting, caloric restriction, and physical activity work together to improve MetS markers, body composition, and lifestyle in adults with MetS in Riyadh. The study will randomly assign 140 participants into two groups one group will follow a program combining intermittent fasting 16 hours fasting, 8 hours eating window, calorie-controlled diet, and at least 150 minutes per week of moderate aerobic exercise the other group will receive the standard care provided by the hospital. The interventions will be monitored over 12 weeks. Participants will be assessed at the start and then every 4 weeks up to 12 weeks for changes in blood glucose, cholesterol, blood pressure, body mass index, physical activity, dietary intake, and sleep quality. Physical activity will be tracked using a mobile app recommended by Saudi Arabias Ministry of Health. The study aims to measure how these lifestyle changes affect metabolic health markers and overall wellbeing in adults with MetS.