Villaviciosa De Odon

Researchers are studying the effects of a supervised exercise program during intensive cancer treatment in adolescents aged 12 to 19 years with newly diagnosed or relapsed malignant extracranial tumors. This study aims to understand how exercise during treatment may benefit heart function and other health factors, focusing on adolescents during their transition to survivorship. The trial is a randomized controlled study conducted in multiple hospitals in Madrid, Spain. Participants are randomly assigned to two groups one receives a supervised exercise program combined with lifestyle counseling, and the other receives standard care with health counseling. The exercise includes three supervised aerobic and resistance sessions per week at the hospital gym, patients rooms during immunodepression phases, or online sessions, plus inspiratory muscle training five days per week. Both groups receive psychological and lifestyle counseling twice monthly. The intervention lasts throughout intensive treatment, approximately 5 to 6 months. Participants undergo assessments at diagnosis, end of treatment, and three months after treatment ends. These include heart function measured by echocardiography, blood pressure, blood lipids, body composition by DXA scans, physical fitness tests, muscle strength, functional mobility, quality of life, fatigue, clinical outcomes like survival and treatment tolerance, as well as biological markers related to metabolism, inflammation, gut microbiome, and immune function. Adherence to exercise is also monitored throughout the study period.

Researchers are investigating whether an 8-week core stabilization training program can improve abdominal strength and knee stability in physically active women aged 18 to 35. The study aims to determine if this training enhances abdominal endurance measured by the Prone Bridge Test and improves knee stability assessed by the Lateral Squat Down, Y-Balance Test, and Drop Vertical Jump. The comparison of results before and after the program will show if strength and stability improve. Participants will be randomly assigned to either an experimental group completing the supervised 8-week core stabilization program or a control group maintaining their usual activity without doing any core stabilization exercises. The training includes progressive front plank, side plank, and Nordic hamstring exercises performed under supervision to ensure proper technique and adherence, following a structured routine described in previous research. During the study, all participants will complete baseline and post-intervention assessments of abdominal endurance and knee stability using standardized tests recorded with a Vicon motion-capture system. Researchers will monitor adherence to the training program and measure changes in dynamic balance, knee control, and landing mechanics. The study duration is 8 weeks, focusing on physical performance and safety for young active women.