Villaviciosa De Odon

Researchers are evaluating the effects of a supervised exercise program alongside lifestyle counseling during intensive treatment for adolescents aged 12 to 19 years with newly diagnosed or relapsed malignant extracranial tumors. This randomized controlled trial involves participants from four hospitals in Madrid, Spain, focusing on improving health, especially heart and metabolic health, during cancer treatment expected to last about 5 to 6 months. The study aims to support better health habits and quality of life as patients transition to survivorship. Participants are randomly assigned to two groups. The intervention group receives supervised exercise sessions three times a week, including aerobic and muscle strength training, conducted in hospital gyms, patient rooms during immunodepression phases, or online if needed. They also perform inspiratory muscle training five days per week. Both groups receive health counseling twice a month, covering psychological support and guidance on activity, sleep, and diet. The control group can visit the gym twice a month for playing activities to maintain engagement. Participants will be assessed at diagnosis, end of treatment (14 to 28 weeks later), and three months after treatment ends. Researchers measure heart function using echocardiography, blood pressure, blood lipids, body composition, physical fitness, muscle strength, mobility, quality of life, cancer-related fatigue, and clinical outcomes like survival and treatment tolerance. They also study biological markers related to metabolism, inflammation, immune function, and the gut microbiome. The study plans to recruit at least 136 adolescents and monitor their health throughout the treatment period and follow-up.

Researchers are investigating whether an 8-week core stabilization training program can improve abdominal strength and knee stability in physically active women aged 18 to 35. The study aims to determine if this training enhances abdominal endurance using the Prone Bridge Test and improves knee stability assessed by the Lateral Squat Down, Y-Balance Test, and Drop Vertical Jump. Participants' performance will be compared before and after the intervention to evaluate any measurable improvements. Participants will follow a supervised 8-week core stabilization program consisting of front plank, side plank, and Nordic hamstring exercises. Each exercise includes specific durations and repetitions, with progressions such as alternating leg lifts and hip abduction. Rest periods between sets range from 30 to 60 seconds based on perceived exertion. Exercises are performed under supervision before regular training sessions. During the study, participants will complete baseline testing of abdominal strength and knee stability using standardized assessments recorded with a Vicon motion-capture system. After the 8-week training, the same tests will be repeated to measure changes. The main outcome is the change in abdominal endurance measured by the Prone Bridge Test from baseline to post-intervention.