Aleppo

This research investigates the knowledge, attitudes, and behaviors related to antibiotic resistance and careful antibiotic use among healthcare workers in Syria. It is a multicenter cross-sectional study designed to gather information across different regions to better understand how healthcare workers perceive and manage antimicrobial resistance. Participants will complete an online questionnaire developed using Google Forms, which includes eight sections based on questions from previous studies. The survey will be distributed through social media in various governorates, and each questionnaire is expected to take about 5 to 10 minutes to finish. The study uses snowball sampling to recruit at least 200 healthcare workers, ensuring a confidence level of 95% with a 5% margin of error. During the study, participants responses will be collected and analyzed using SPSS software. Researchers will measure healthcare workers knowledge, attitudes, and practices regarding antimicrobial resistance by reviewing questionnaire answers. The study will continue until June 2025, and all data handling and analysis will aim to provide insights into improving antibiotic use practices among healthcare professionals.

Researchers are evaluating the impact of antibiotic prophylaxis on reducing wound infection rates after open repair surgery for primary elective groin hernias in high-risk patients. This randomized controlled trial focuses on patients considered high risk due to factors like age, diabetes, obesity, immune system status, or other health issues. The study aims to determine if giving antibiotics before surgery lowers the chance of wound infections and related complications. Participants will be randomly assigned to one of two groups one group will receive a single preoperative dose of the antibiotic Cefazolin 1 gram, while the other group will not receive any antibiotic prophylaxis. The study compares these groups to assess the effectiveness of antibiotic use in preventing postoperative wound infections following the hernia repair surgery. During the study, participants will be monitored for up to 30 days after surgery for any wound or surgical site infections and overall complications. Researchers will also track secondary outcomes such as mortality rates and length of hospital stay. The study involves regular follow-up visits to assess recovery and any adverse events, ensuring safety and accurate data collection throughout the 30-day postoperative period.