+1 877 705 191424 / 7
HIPAA Compliant
ISO 27001 Certified

Search Bar & Filters

Found 4 Actively Recruiting clinical trials

P

Actively Recruiting

Researchers are evaluating whether measuring peripheral venous pressure PVP can better guide the need for diuretic treatment and improve long-term outcomes such as mortality, hospital readmissions, and emergency visits in patients hospitalized with heart failure compared to standard evaluation methods. This study focuses on adults aged 18 to 99 with new or worsened chronic heart failure, regardless of heart function or cause. The trial aims to address the challenge of persistent congestion after hospital discharge, which contributes to high readmission and death rates. Participants will be randomly assigned to two groups one receiving diuretic therapy guided by PVP measurements aiming for a PVP less than 9 mmHg before discharge, and the other receiving standard diuretic therapy based on physician judgment. Peripheral IV lines will be placed to measure PVP using a defined procedure, and treatment will follow European Society of Cardiology guidelines. Patients unable to have PVP measured or requiring intensive support will be excluded. The study will last one year, with follow-up to track major adverse events including death and hospital readmissions. During the study, participants will undergo blood sampling, electrocardiogram, echocardiogram, daily monitoring of fluid intake and output, weight, and biochemistry tests. Data will be collected electronically, and PVP measurements taken at admission and before discharge will be analyzed for correlation with outcomes. Researchers will also evaluate kidney function changes and hospitalization patterns. The study involves 650 participants and includes statistical analyses to compare the two treatment approaches over one year.

Age: 18Years - 99YearsAll GendersPhase 4
16 locations
E

Actively Recruiting

Healthy Volunteer

Researchers are investigating the effects of a structured breastfeeding education program on infants who experience nipple refusal, as well as on maternal breastfeeding motivation and mother-infant bonding. This randomized controlled trial focuses on mothers with infants aged 1 to 6 months who have faced nipple refusal for at least 3 days and up to 30 days. The main goal is to see if the education improves infants sucking skills and strengthens the bond and motivation of breastfeeding mothers. Participants will be randomly assigned to either an intervention group or a control group. Mothers in the intervention group will receive a one-week structured breastfeeding education supported by midwives, covering topics like breastfeeding techniques, nipple refusal management, milk production, skin-to-skin contact, bonding, and motivation strategies. After this education, they will get daily online support for 15 days, during which breastfeeding progress is closely monitored. The control group will receive routine postpartum care without the structured education but will be given educational materials after the study ends. Throughout the study, mothers demographic information, infants sucking skills, mother-infant bonding, and breastfeeding motivation will be evaluated at the start and again after 16 days. Daily observation forms will track breastfeeding progress during the follow-up. The primary outcome measured is the Breastfeeding Motivation Scale, and maternal attachment will also be assessed. The total participation involves a baseline evaluation, one week of education for the intervention group, followed by a 15-day support and observation period.

Age: 18Years - 45YearsFEMALEPhase Not Applicable
1 location
E

Actively Recruiting

Healthy Volunteer

Researchers are studying the effects of the Breastfeeding Self-Efficacy Resources Development Nurse Consultancy Program EMZGEDAP, which is based on Denniss Breastfeeding Self-Efficacy Theory and hypnobreastfeeding philosophy. This study focuses on pregnant women and their close family members to see how this program influences social support perception, breastfeeding confidence, and breastfeeding outcomes. The study compares an intervention group receiving the program to a control group receiving routine hospital care. The intervention involves individual counseling sessions lasting a total of 7.5 hours, divided into five sessions two with the mother and her family relatives together, two with the mother alone, and one with the family relatives alone. The program uses techniques such as affirmations, relaxation, breathing exercises, and educational methods like presentations, role-playing, and peer discussions to support breastfeeding self-efficacy and bonding. Participants will be assessed before birth and at 1, 3, and 6 months postpartum using various scales measuring breastfeeding self-efficacy, social support perception, and breastfeeding and nutrition results. These assessments include the Antenatal Breastfeeding Self-Efficacy Scale, Postpartum Breastfeeding Self-Efficacy Scale, and scales for perceived support from close others. The study aims to monitor how the program affects breastfeeding success and the support mothers receive during this time.

Age: 18Years - 65YearsAll GendersPhase Not Applicable
1 location
I

Actively Recruiting

Researchers are studying the effects of colostomy care training based on Jeffries Simulation Theory on nursing students. This study aims to evaluate how this training impacts students knowledge, skills, stress, self-efficacy, readiness, state anxiety, satisfaction, and self-confidence. The study compares students who receive different types of colostomy care training to understand which method better supports learning and confidence. Participants are divided into two groups. The intervention group receives individual training in a simulation laboratory using mannequins and standardized simulated patients to practice colostomy care skills. The control group practices colostomy bag change and care using a low-fidelity patient model. All students receive training based on a Colostomy Care Training Booklet prepared by the researchers. During the study, nursing students knowledge, skills, stress, self-efficacy, readiness, anxiety, satisfaction, and confidence are assessed within one week after the simulation exercises. These outcomes are measured to evaluate the effectiveness of the training. The study uses a randomized, double-blind design to compare results between the intervention and control groups, ensuring careful monitoring of student progress.

Age: 18Years +All GendersPhase Not Applicable
1 location