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Found 26 Actively Recruiting clinical trials
Actively Recruiting
Healthy Volunteer
This research aims to compare daily living activities and upper body exercise capacity between individuals with high body mass index BMI and those with normal BMI. Participants include adults aged 18 to 65 years with varying BMI levels. The study focuses on understanding how body weight differences relate to physical function and fatigue. Participants are grouped into those with a BMI of 25 kgm2 or greater and those with a BMI between 18.5 and 24.9 kgm2. The study observes their upper extremity exercise capacity and daily living activities on the first day. Fatigue and pain levels are also assessed as secondary measures. During the study, participants will undergo tests to measure their upper body exercise ability and daily activity performance. Researchers will evaluate fatigue and pain on the first day to understand physical function differences. Individuals volunteer for the study and cooperate with physical tests, with monitoring to ensure accurate data collection. The study is expected to continue until December 2025.
Actively Recruiting
Understanding Heart Disease Risks and Healthy Lifestyle Habits in Adults with Ankylosing Spondylitis
Researchers are evaluating the knowledge patients with ankylosing spondylitis have about cardiovascular disease risk factors and healthy lifestyle behaviors. This observational study aims to fill a gap in existing research by assessing how well these patients understand risks related to cardiovascular health and their engagement in physical activity. The study is sponsored by Kirsehir Ahi Evran Universitesi and focuses on adults aged 18 to 65 with this condition. Participants include patients diagnosed with ankylosing spondylitis who have been on stable medication for at least three months. The study involves assessing their knowledge of cardiovascular risk factors and healthy lifestyle behaviors through questionnaires. Physical activity levels, cardiovascular risk, and other comorbidities are also evaluated as part of the study measures. During the study, participants will complete assessments lasting between 5 to 15 minutes each, covering knowledge of cardiovascular disease risks, lifestyle behaviors, physical activity, and related health risks. These evaluations help researchers understand patient awareness and habits. The total duration of participation varies, with no intervention or treatment administered. The study is observational, focusing on data collection and analysis without altering patient care.
Actively Recruiting
Healthy Volunteer
Researchers are evaluating different exercise approaches for people with subacromial impingement syndrome SAIS, a common shoulder condition causing pain, limited movement, muscle weakness, and reduced quality of life. This randomized controlled trial compares physiotherapist-supervised rehabilitation with home exercise programs, aiming to provide evidence about which approach works better. The study involves 63 adults aged 30 to 65 diagnosed with SAIS and includes a control group for comparison. Participants will be randomly assigned to one of three groups supervised rehabilitation, home exercise, or control. The supervised group will attend physiotherapy sessions five days a week for four weeks, including pain management, stretching, range of motion, scapular stabilization, strengthening exercises, and activity training. The home exercise group will receive training and then perform a structured exercise program independently at home for four weeks. The control group will not receive any intervention during the study but will be offered supervised rehabilitation after the study period. During the study, researchers will assess pain levels, upper limb function, shoulder movement range, grip strength, sleep quality, and overall quality of life at the start and after four weeks. Evaluations use tools like the Visual Analog Scale for pain, DASH questionnaire for function, goniometer for motion, dynamometer for strength, a sleep quality scale, and WHOQOL-BREF for life quality. This study aims to guide treatment decisions for managing SAIS by comparing supervised and home-based exercises under careful monitoring.
Actively Recruiting
Obesity is a widespread, preventable health concern. This research aims to compare the effects of two types of exercisehigh intensity interval training and moderate intensity continuous trainingon young women with obesity. The study focuses on how these exercise methods influence body fat percentage, metabolic markers including serum omentin, leptin, and adiponectin, as well as sleep quality and overall life quality. Female participants aged 18 to 45 with a body mass index between 30 and 40 kgm are randomly assigned to one of two exercise groups. One group performs high intensity interval training on a bicycle ergometry device, involving intervals at increasing intensities over 8 weeks, five days per week. The other group engages in moderate intensity continuous cycling exercise for 30 minutes per session, also five days weekly for 8 weeks. Both exercise routines include warm-up and cool-down periods. Participants undergo blood tests at the start and end of the study to measure serum adipokine levels. Anthropometric measurements and body fat percentages are recorded, alongside questionnaires assessing sleep and quality of life. Data analysis will be conducted using statistical software. The study monitors outcomes over the 8-week exercise period to evaluate the effects of the two exercise types on obesity-related health indicators and wellbeing.
Actively Recruiting
Rotator cuff lesions are a common cause of shoulder pain and reduced function, especially in middle-aged and older adults. This trial investigates the effects of Mobilization with Movement MWM, a manual therapy technique, on pain, function, and shoulder joint position sense in people with rotator cuff lesions. Researchers aim to find out if MWM offers benefits beyond conventional physiotherapy or task-oriented virtual reality training for improving shoulder health and proprioception. Participants with rotator cuff lesions will be randomly assigned to one of three groups the MWM group receiving manual therapy combined with active, pain-free shoulder movements the conventional physiotherapy group receiving standard exercises and physical therapy without MWM techniques or the control group engaging in task-oriented training through virtual reality exercises simulating daily activities. Treatments will be delivered by trained physiotherapists following standardized protocols over an 8-week intervention period. Participants will be evaluated before and after the intervention using the Quick Disabilities of the Arm, Shoulder and Hand QuickDASH questionnaire to assess functional disability, pain intensity scales, and a shoulder joint position sense test involving active repositioning with a laser pointer. The study will also monitor changes in proprioceptive accuracy and shoulder function to determine MWMs role in conservative rehabilitation. All procedures are conducted under ethical standards with informed consent, and the trial concludes with assessments after the 8-week program.
Actively Recruiting
This research aims to evaluate the effectiveness of adding core stabilization exercises to conventional physical therapy for patients aged 40 to 60 with partial tears of the rotator cuff. The study investigates how these targeted core exercises compare to classic trunk and abdominal muscle strengthening in improving pain, shoulder function, and clinical recovery. Rotator cuff tears often result from repetitive strains and muscle imbalances, affecting not just the shoulder but also trunk control and posture, which are crucial for shoulder stability. Participants are divided into three groups one group receives conventional shoulder rehabilitation five days a week for four weeks plus core stabilization exercises three days a week another group receives the same conventional rehabilitation combined with classic trunk and abdominal strengthening exercises three days a week and the third group receives only conventional rehabilitation five days a week for four weeks. Core stabilization sessions include gradually progressing exercises supervised by a physical therapist, focusing on maintaining lumbar and pelvic neutral positions. The classic strengthening program involves established Williams and McKenzie exercises. During the study, participants will undergo assessments of pain using a Visual Analog Scale, tendon thickness, shoulder pain and disability index, range of motion, and core muscle strength at the start, end of treatment week 3, and follow-up week 12. The study tracks changes in these measures to evaluate the clinical effects of the exercise programs. The entire participation lasts for 12 weeks, including treatment and follow-up evaluations to monitor recovery and function improvements.
Actively Recruiting
Researchers are evaluating the effects of basic and functional respiratory muscle training on pain, disability, and functionality in people with non-specific chronic low back pain lasting at least 3 months. The study randomly assigns participants to one of three groups to compare different treatment combinations over 10 weeks. The aim is to better understand how these therapies impact pain levels, disability, physical activity, and quality of life. Participants will be divided into three groups one receiving only classical physiotherapy, the second combining classical physiotherapy with foundation inspiratory muscle training, and the third combining classical physiotherapy with functional inspiratory muscle training. Physiotherapy includes hotpack, ultrasound, TENS, and basic exercises over 30 face-to-face sessions. The muscle training groups also perform home exercises twice daily, monitored with diaries, with intensity adjusted weekly. Assessments occur before treatment, after 30 sessions, and at 3 months, 6 months, and 1 year. Researchers will measure pain intensity, disability, respiratory muscle strength, and muscle thickness, among other outcomes. Physical tests include aerobic capacity, flexibility, muscle strength, core endurance, and postural control. Questionnaires will evaluate quality of life, fear of movement, anxiety, depression, and treatment satisfaction. This comprehensive monitoring aims to track progress and safety throughout the study duration.
Actively Recruiting
Carpal tunnel syndrome CTS is a common condition caused by compression of the median nerve in the wrist, leading to symptoms like pain, numbness, and tingling in the fingers. This research aims to compare different treatment methods for CTS, focusing on the effects of corticosteroid injections, nerve hydrodissection with saline, and exercise therapy, to find the most suitable approach for patients experiencing nerve compression in the wrist. Both men and women aged 18 to 65 with CTS are invited to participate in this study. The study involves three groups one receiving corticosteroid injections with tendon and nerve gliding exercises, another receiving saline hydrodissection with the same exercises, and a third group performing only the exercises. Injections are performed under ultrasound guidance to target the median nerve accurately. Exercises include specific hand and wrist positions to improve tendon and nerve mobility, done daily for three weeks. The study compares these treatments over a 12-week period. Participants will be evaluated at the start, at three weeks, and at 12 weeks after treatment begins. Assessments include nerve conduction studies, pain questionnaires, functional questionnaires, and ultrasound measurements of the median nerve area. Researchers will monitor symptoms, nerve function, and nerve size to understand how each treatment affects CTS. The total study duration for each participant is 12 weeks, with a focus on safety and effectiveness of the treatments.
Actively Recruiting
Researchers are evaluating the effectiveness of extracorporeal shock wave therapy ESWT combined with eccentric exercise compared to eccentric exercise alone in treating athletes with patellar tendinopathy PT. The study aims to see how adding ESWT to a 6-week exercise program affects clinical outcomes such as pain, function, and physical performance. This trial is randomized and single-blind, involving professional and recreational athletes who experience patellar tendon pain related to training or physical activity. Participants will be divided into two groups one receiving focused ESWT three times a week alongside a 6-week eccentric exercise program, and the other performing the exercise program alone for 6 weeks. The eccentric exercise involves single-leg squats on a 25 incline board, done twice daily for three sets of 15 repetitions, five days a week. ESWT is applied once weekly for three weeks using specific dosing parameters appropriate to pain levels. No exercise is performed on ESWT treatment days. Participants will be evaluated at baseline, 3 weeks, 6 weeks, and then at 3, 6, and 12 months. Assessments include sociodemographic data, pain levels using the Visual Analog Scale VAS, tendon pain and function via the VISA-P questionnaire, physical capacity tests like maximal vertical jump, single-leg hop distance, and single-leg squat on an incline board. Additional measures include pain catastrophizing, fear of movement, quality of life, and activity level. Participants will keep an exercise diary to monitor adherence. The study lasts up to 12 months after treatment to track outcomes and safety.
Actively Recruiting
Healthy Volunteer
Researchers are evaluating the effect of applying a hot compress to the intestines during abdominal surgery on postoperative nausea, vomiting, and bowel function. This randomized study involves patients undergoing abdominal surgery who meet specific criteria such as age and body mass index BMI. The study aims to determine whether covering the intestines with saline heated to 36C during surgery affects recovery outcomes like nausea and bowel function. Participants are randomly assigned to one of two groups. The intervention group will have their intestines covered with sterile gauze soaked in saline heated to 36C during surgery to prevent drying and reduce infection risk. The control group will receive standard care, with intestines covered using gauze soaked in unheated saline. Both groups will undergo routine preoperative and postoperative procedures. Initially, 30 patients per group will be included, with further enrollment based on power analysis. Throughout the study, participants will complete forms and scales including the Patient Introduction Form, Patient Follow-up Form, Quality of Recovery-15 Scale QoR-15, and Gastrointestinal Symptom Rating Scale GSRS. Researchers will monitor gastrointestinal function by measuring time to first gas passage, first bowel movement, first normal bowel sounds, and first intake of liquid or semi-solid food. Postoperative gastrointestinal symptoms such as nausea, bloating, pain, and vomiting will also be assessed. The study will continue until early 2026, with careful monitoring of recovery and symptom severity.
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