Alamogordo

Researchers are conducting an international, multicenter observational study to better understand subpopulations of patients with Autism Spectrum Disorder ASD. The study aims to identify sufficient biological and clinical markers that can help distinguish groups of patients who may respond best to specific medications. This research is sponsored by Stalicla SA and focuses on participants aged 12 to 65 years with a prior ASD diagnosis. This study does not involve any specific treatment but collects detailed clinical and molecular data from participants. Participants provide information through their health records and input from parents or reliable caregivers. The study characterizes ASD subpopulations based on clinical and molecular markers gathered at the start of the study. Participants will be involved in providing health history and molecular data on day 0 of the study. Researchers will analyze this information to define ASD subgroups. There are no interventional treatments, and safety monitoring involves excluding participants with recent fever or medical conditions that might interfere with study completion. The study runs until May 2027, allowing comprehensive data collection and analysis over time.

Researchers are studying whether parent-mediated behavior therapy for children with autism spectrum disorder ASD can be equally effective when delivered via telehealth compared to in-person sessions. The trial focuses on children aged 2 to 7 years who display challenging behaviors such as self-injury or aggression. The study is sponsored by Stanford University and aims to assess the best way to support families managing these behaviors. Caregivers will participate in either in-person or telehealth coaching sessions for behavior therapy, each lasting one hour weekly over 12 weeks. Another group will complete online psychoeducation modules for the same duration and frequency. The study includes three groups in-person behavior therapy, telehealth-enabled behavior therapy, and psychoeducation as a comparator. Participants will be monitored through assessments of the frequency of challenging behaviors and parental stress at 4-week intervals. Caregivers must be available for weekly sessions at home during weekdays and have reliable cell phone coverage. The study will measure outcomes over the 12-week intervention period and monitor caregiver adherence to the treatment plan.