Actively Recruiting

Age: 0 - 16Years
All Genders
Healthy Volunteers
NCT07530354

A Longitudinal Cohort Study on the Changes of Physiological Mechanisms in Children After Biliary Tract Reconstruction

Led by Wuhan Children's Hospital · Updated on 2026-04-15

100

Participants Needed

3

Research Sites

521 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Through observational studies, the long-term changes in liver function, metabolic state, immune response and other aspects of children after biliary tract reconstruction during their growth process were systematically explored. The risks of these long-term physiological changes on chronic diseases such as cardiovascular diseases, diabetic diseases and liver cirrhosis in adulthood, as well as their impacts on cognitive function, musculoskeletal health and other aspects were evaluated. How do early physiological changes affect a patient's long-term health? Are there any potential biomarkers that can predict future health outcomes? Based on the research results, preventive and intervention measures that are helpful in reducing the risk of long-term complications are proposed.

CONDITIONS

Official Title

A Longitudinal Cohort Study on the Changes of Physiological Mechanisms in Children After Biliary Tract Reconstruction

Who Can Participate

Age: 0 - 16Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy children matched by age and gender were selected as the control group
Not Eligible

You will not qualify if you...

  • Children with other serious diseases such as cancer or autoimmune diseases
  • Children with obvious liver function abnormalities before surgery
  • Children undergoing other major treatments

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

Wuhan Children's Hospital

Wuhan, Hubei, China, 430016

Actively Recruiting

2

Wuhan Children'S Hospital

Wuhan, Hubei, China, 430016

Actively Recruiting

3

Wuhan Children'S Hospital

Wuhan, Hubei, China, 430016

Actively Recruiting

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Research Team

X

Xueqiang Yan

CONTACT

J

Jing Zhang

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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A Longitudinal Cohort Study on the Changes of Physiological Mechanisms in Children After Biliary Tract Reconstruction | DecenTrialz