Actively Recruiting

All Genders
NCT00315380

Longitudinal Study for Eosinophilic Granulomatosis With Polyangiitis

Led by University of Pennsylvania · Updated on 2026-01-23

700

Participants Needed

13

Research Sites

1182 weeks

Total Duration

On this page

Sponsors

U

University of Pennsylvania

Lead Sponsor

G

GlaxoSmithKline

Collaborating Sponsor

AI-Summary

What this Trial Is About

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare immune system disorder that causes asthma, an excessive number of eosinophils (a type of white blood cell) in the blood, and the inflammation of blood vessels, or vasculitis. In order to properly treat EGPA, it is critical that the level of disease activity can be determined over the course of the disease. The purpose of this study is to determine new biological markers, or biomarkers, that may be used to assess the severity of this disease in people with EGPA.

CONDITIONS

Official Title

Longitudinal Study for Eosinophilic Granulomatosis With Polyangiitis

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with a diagnosis of eosinophilic granulomatosis with polyangiitis
  • Parent or guardian willing to provide informed consent, if applicable
Not Eligible

You will not qualify if you...

  • Inability to give informed consent and to sign the consent form

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 13 locations

1

University of California San Diego

San Diego, California, United States, 92122

Completed

2

National Jewish Health

Denver, Colorado, United States, 80206

Completed

3

Brigham and Women's Hospital

Boston, Massachusetts, United States, 02215

Completed

4

Mayo Clinic

Rochester, Minnesota, United States, 55905

Completed

5

Cleveland Clinic Foundation

Cleveland, Ohio, United States, 44195

Completed

6

University of Pennsylvania

Philadelphia, Pennsylvania, United States, 19104

Completed

7

University of Pittsburgh

Pittsburgh, Pennsylvania, United States, 15260

Completed

8

University of Utah

Salt Lake City, Utah, United States, 84112

Completed

9

St. Joseph's Healthcare

Hamilton, Ontario, Canada

Actively Recruiting

10

Mount Sinai Hospital

Toronto, Ontario, Canada

Completed

11

medius KLINIK KIRCHHEIM

Kirchheim unter Teck, Germany, 73230

Actively Recruiting

12

AOU Meyer IRCCS

Florence, Italy

Actively Recruiting

13

Imperial College Healthcare NHS Trust/ Imperial College London

London, United Kingdom, W12 0NN

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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