Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT01851642

Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs

Led by University of Florida · Updated on 2025-11-06

220

Participants Needed

1

Research Sites

1353 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to look at how Alpha-1-antitrypsin (AAT) deficiency and Cystic Fibrosis (CF) affect white blood cells in the lungs, called macrophages, and their ability to work.

CONDITIONS

Official Title

Lung Disease and Its Affect on the Work of White Blood Cells in the Lungs

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed informed consent
  • Male or female 18 years of age or older
  • Negative pregnancy test for women of childbearing potential
  • Hemoglobin >12.5 g/dl measured on the day of participation
  • Negative urine nicotine test
Not Eligible

You will not qualify if you...

  • Pregnancy or breastfeeding
  • Weight < 50 kg
  • History of anemia requiring blood transfusions, erythropoietin supplementation, or iron supplementation within the past 36 months
  • Known hemoglobin <12.5 g/dl within the past 90 days
  • Systolic blood pressure > 180 mmHg and/or diastolic blood pressure >100 mmHg
  • Poor venous access
  • Large volume blood donation (>200 ml or 7 ounces) within the previous 56 days
  • Clinically significant cardiac, hemostatic or neurological impairment or any other significant medical condition affecting safety
  • Psychiatric or cognitive disturbance or illness affecting safety
  • Current smoker

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Shands at the University of Florida

Gainesville, Florida, United States, 32610

Actively Recruiting

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Research Team

A

Allison E. Faunce, B.A.

CONTACT

M

Michelle Owens, RN, BSN

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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