Actively Recruiting

Age: 18Years +
All Genders
ID07396636

Machine Learning-Assisted Intraoperative Hypotension Management: Developing Personalized Treatment Recommendations

Led by Nevsehir Public Hospital · Updated on 2026-04-09

50

Participants Needed

1

Research Sites

8 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating intraoperative hypotension, which is a drop in blood pressure during surgery under general anesthesia. This condition is common and may reduce blood flow to vital organs, leading to complications after surgery. The study aims to improve understanding of this condition by collecting detailed blood pressure and heart function data and analyzing it with machine learning to identify different patterns and causes of hypotension. The study observes adult patients undergoing planned surgeries lasting at least two hours with continuous invasive arterial blood pressure monitoring. During surgery, detailed hemodynamic measurements such as cardiac output, stroke volume, and vascular resistance are recorded regularly. When low blood pressure occurs, its timing, severity, and treatments like fluids or medications are noted. The study does not change patient care but collects data to analyze treatment responses and physiological subtypes of hypotension. Participants will have their blood pressure and heart function continuously monitored during surgery. The study gathers information on treatments used and how quickly blood pressure recovers. Researchers will analyze relationships between patient factors like age, sex, and health conditions with hypotension episodes. The main outcome is classifying hypotension subtypes during surgery, aiming to support future personalized treatment recommendations. Data privacy and ethical standards are maintained throughout the study.

CONDITIONS

Brief Title

Machine Learning-Assisted Management of Intraoperative Hypotension for Personalized Treatment

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients aged 18 years or older
  • Scheduled for elective surgical procedures
  • Surgery performed under general anesthesia
  • Continuous invasive arterial blood pressure monitoring during surgery
  • Planned surgery duration of at least 2 hours
  • Able to provide written informed consent
Not Eligible

You will not qualify if you...

  • Emergency surgery
  • Diagnosis of sepsis, septic shock, or advanced cardiogenic shock
  • Cardiac rhythm disturbances preventing reliable hemodynamic measurements (e.g., atrial fibrillation)
  • Severe left ventricular dysfunction or advanced heart failure (ejection fraction below 30%)
  • Inability to maintain intraoperative arterial cannulation
  • Inability to provide informed consent (e.g., cognitive impairment or refusal)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Monitoring

Duration - Intraoperative period (from anesthesia induction to the end of surgery)

Participants undergo continuous hemodynamic monitoring during elective surgery under general anesthesia to record detailed blood pressure and cardiac function data.

1 surgical procedure with continuous monitoring

Trial Site Locations

Total: 1 location

1

Konya City Hospital

Konya, Konya/Meram, Turkey (Türkiye), 42040

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Research Team

M

Mehmet Akif Yazar, MD, PhD, Assoc. Prof.

E

Elif Korkmaz Ozturk, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Frequently Asked Questions

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