Actively Recruiting
Effects of Progressive Barbell Strength Training on Cardiovascular and Metabolic Health Markers
Led by Mayo Clinic · Updated on 2026-05-11
200
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of a 12-week coached Starting Strength barbell training program on blood pressure and other cardiovascular and metabolic health markers. This study focuses on adults aged 18 to 100 years who are sedentary or minimally active and aims to understand how strength training may influence systolic and diastolic blood pressure, cholesterol levels, and fasting glucose. Participants will engage in a progressive barbell strength training program conducted by certified Starting Strength coaches. The program involves core barbell movements such as squats, deadlifts, bench presses, overhead presses, and power cleans, performed three times per week for about 60 minutes per session over 12 weeks. Training sessions will be held at a designated gym. During the study, participants will undergo blood pressure measurements and laboratory tests before and after the 12-week training, including assessments of cholesterol fractions and fasting glucose. Researchers will monitor changes from baseline to 16 weeks to evaluate the program's effects. Participants will be asked to commit to regular training sessions and provide laboratory test results from the same company before and after the intervention.
CONDITIONS
Brief Title
A Study Of Starting Strength Barbell Training
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18-100 years
- Sedentary or minimally active (less than 150 minutes of moderate-intensity physical activity per week)
- No participation in structured resistance training programs within the past 6 months
- Able to safely participate in resistance training as determined by medical screening
- Willing to commit to 3 training sessions per week for 12 weeks
- Able to provide informed consent
- Willing to obtain pre- and post-intervention laboratory tests from the same laboratory company
You will not qualify if you...
- Current participation in structured resistance training programs
- Cardiovascular disease requiring activity restriction
- Uncontrolled hypertension (systolic BP >180 mm Hg or diastolic BP >110 mm Hg)
- Musculoskeletal conditions precluding safe barbell training
- Changes in lipid-lowering or antihypertensive medications within 3 months prior to enrollment
- Known cardiovascular, metabolic, or renal disease that would preclude safe participation in resistance training
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 12 weeks
Participants engage in a 12-week progressive barbell strength training program coached by certified Starting Strength coaches.
Training sessions 3 days per week, approximately 60 minutes each
Trial Site Locations
Total: 1 location
1
Mayo Clinic in Arizona
Scottsdale, Arizona, United States, 85259
Actively Recruiting
Research Team
J
Joshua Lee, PA-C,MPAS
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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