Actively Recruiting

FEMALE
Healthy Volunteers
ID06879080

Maternal Iron Deficiency and Childhood Health - a Prospective Cohort Study

Led by Tampere University Hospital · Updated on 2025-03-17

6000

Participants Needed

1

Research Sites

365 weeks

Total Duration

On this page

Sponsors

T

Tampere University Hospital

Lead Sponsor

T

Tampere University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are studying how maternal iron deficiency and iron deficiency anemia, along with the use of iron supplements during pregnancy, affect the health and development of children up to seven years old. This prospective observational cohort study involves pregnant women who visit Tampere University Hospital for prenatal care or labor. The study also includes two smaller groups focusing on mothers with iron deficiency or diabetes to explore how maternal iron status relates to the child's iron levels and development. All pregnant women who agree to participate complete an online questionnaire about their anemia diagnosis, iron supplement use, chronic diseases, and any intravenous iron treatments during pregnancy. The mothers' iron status is tested before delivery, and their children's iron levels are checked at birth, a few days after birth, and again at 8 months, 2 years, and 5 years. Parents also fill out questionnaires about their child's nutrition, sleep, behavior, and development at these same ages. Participants' health records will be followed from birth until the child is seven years old to gather information on growth, diagnoses, medications, and support needs at school. Data collection began in April 2024 and will continue for about 3.5 years, with ongoing follow-up of children through outpatient records. The study aims to provide insights that could guide pregnancy care and future recommendations for diagnosing and treating iron deficiency in mothers and children.

CONDITIONS

Brief Title

Maternal Iron Deficiency and Childhood Health

Who Can Participate

FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant
  • Can read and write Finnish, Swedish or English
Not Eligible

You will not qualify if you...

  • Illiterate

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - Up to 3.5 years during recruitment

Participants are screened for eligibility to participate in the trial.

Prenatal visits or hospital visits for labor

Diagnostic Evaluation

Duration - From pregnancy through delivery and up to 1 month of age for newborns

Participants' iron status and health data are collected from mothers and newborns through questionnaires, lab tests, and medical records.

1 visit for hemoglobin and iron status testing before delivery, cord blood and newborn tests at birth and 2-5 days of age

Long-term Monitoring

Duration - From birth until 7 years of age

The child's health and development are followed through medical records and questionnaires at multiple ages.

Questionnaires and lab tests at 8 months, 2 years, and 5 years; health record reviews at 1.5, 4, and 7 years

Trial Site Locations

Total: 1 location

1

Tampere University Hospital

Tampere, Pirkanmaa, Finland, 33520

Actively Recruiting

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Research Team

L

Laura K Seppälä, MD,PhD

E

Elli Toivonen, MD,PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

4

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