Actively Recruiting

Age: 18Years +
All Genders
ID06296277

Management of Mechanical Ventilation During Surgery: an International, Multicenter, and Observational Data Registry

Led by Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria · Updated on 2026-05-28

10000

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

A

Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria

Lead Sponsor

U

University Of Perugia

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research is an international, multicenter, prospective, cross-sectional study focusing on adults undergoing surgery with intraoperative mechanical ventilation. It aims to describe the rate and types of lung-related complications after surgery, patient characteristics, ventilation management during surgery, and any adverse events during ventilation. The study also seeks to understand how intraoperative mechanical ventilation is practiced worldwide. Participants include adult patients receiving invasive mechanical ventilation during general anesthesia for surgery. The study collects data during a specific 7-day period chosen by each hospital within 8 weeks of ethics approval. Data includes patient demographics, ventilation settings, and intraoperative events, without introducing new treatments or interventions. Participants’ information will be recorded through electronic case forms, covering ventilation details and outcomes. Researchers will assess lung complications within the first 5 days after surgery as the primary measure, along with adverse events during surgery, ventilation practices, and health outcomes up to 28 days post-surgery. The study aims to improve understanding of ventilation effects and postoperative risks in surgical patients.

CONDITIONS

Brief Title

Mechanical Ventilation in Surgical Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults
  • Receiving intraoperative invasive mechanical ventilation via tracheal intubation or supraglottic device during general anesthesia for surgery
Not Eligible

You will not qualify if you...

  • Receiving intraoperative invasive mechanical ventilation outside of an operating room
  • Receiving intraoperative invasive mechanical ventilation during extracorporeal life support

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Monitoring

Duration - During surgery

Participants are observed during surgery while receiving intraoperative mechanical ventilation. Data about ventilation practices and intraoperative events are collected.

1 visit (intraoperative observation)

Surveillance

Duration - 5 days post surgery

Participants are monitored for postoperative pulmonary complications and other clinical outcomes in the first 5 days after surgery.

Daily assessments for up to 5 days

Long-term Monitoring

Duration - Up to 28 days post surgery

Participants’ postoperative outcomes including ICU admission, hospital length of stay, and mortality are monitored up to 28 days after surgery.

Follow-up assessments as per routine hospital care

Trial Site Locations

Total: 1 location

1

Azienda Ospedaliero Universitaria di Alessandria

Alessandria, Italy, Italy

Actively Recruiting

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Research Team

G

Gianmaria Cammarota, Prof

R

Rachele Simonte, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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