Actively Recruiting
Management of Mechanical Ventilation During Surgery: an International, Multicenter, and Observational Data Registry
Led by Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria · Updated on 2026-05-28
10000
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
A
Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria
Lead Sponsor
U
University Of Perugia
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research is an international, multicenter, prospective, cross-sectional study focusing on adults undergoing surgery with intraoperative mechanical ventilation. It aims to describe the rate and types of lung-related complications after surgery, patient characteristics, ventilation management during surgery, and any adverse events during ventilation. The study also seeks to understand how intraoperative mechanical ventilation is practiced worldwide. Participants include adult patients receiving invasive mechanical ventilation during general anesthesia for surgery. The study collects data during a specific 7-day period chosen by each hospital within 8 weeks of ethics approval. Data includes patient demographics, ventilation settings, and intraoperative events, without introducing new treatments or interventions. Participants’ information will be recorded through electronic case forms, covering ventilation details and outcomes. Researchers will assess lung complications within the first 5 days after surgery as the primary measure, along with adverse events during surgery, ventilation practices, and health outcomes up to 28 days post-surgery. The study aims to improve understanding of ventilation effects and postoperative risks in surgical patients.
CONDITIONS
Brief Title
Mechanical Ventilation in Surgical Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults
- Receiving intraoperative invasive mechanical ventilation via tracheal intubation or supraglottic device during general anesthesia for surgery
You will not qualify if you...
- Receiving intraoperative invasive mechanical ventilation outside of an operating room
- Receiving intraoperative invasive mechanical ventilation during extracorporeal life support
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - During surgery
Participants are observed during surgery while receiving intraoperative mechanical ventilation. Data about ventilation practices and intraoperative events are collected.
1 visit (intraoperative observation)
Duration - 5 days post surgery
Participants are monitored for postoperative pulmonary complications and other clinical outcomes in the first 5 days after surgery.
Daily assessments for up to 5 days
Duration - Up to 28 days post surgery
Participants’ postoperative outcomes including ICU admission, hospital length of stay, and mortality are monitored up to 28 days after surgery.
Follow-up assessments as per routine hospital care
Trial Site Locations
Total: 1 location
1
Azienda Ospedaliero Universitaria di Alessandria
Alessandria, Italy, Italy
Actively Recruiting
Research Team
G
Gianmaria Cammarota, Prof
R
Rachele Simonte, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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