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ID05376891

Disease Registry on Patients With Advanced NSCLC Harboring METex14 Skipping Alterations MOMENT

Led by EMD Serono Research & Development Institute, Inc. · Updated on 2026-05-08

700

Participants Needed

64

Research Sites

N/A

Total Duration

On this page

Sponsors

E

EMD Serono Research & Development Institute, Inc.

Lead Sponsor

M

Merck KGaA, Darmstadt, Germany

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are collecting data on adults with advanced non-small cell lung cancer NSCLC who have a specific genetic change called METex14 skipping alterations. This observational disease registry aims to track real-world treatment patterns, safety, and outcomes over time without changing the usual clinical care. The study is sponsored by EMD Serono Research Development Institute, Inc. and follows participants for up to about 4.9 years. Participants with advanced NSCLC receiving standard systemic therapies as decided by their doctors will be included in this registry. The study does not provide any specific treatments or procedures. Instead, it gathers information from routine clinical care starting at enrollment and continuing until death, loss to follow-up, enrollment in another clinical trial, or the registry ends. Throughout the study, researchers will collect data on tumor response using standard evaluations, overall survival, and any adverse events or reactions experienced by participants. Data collection occurs regularly for nearly five years, allowing the team to monitor changes in treatment and patient outcomes over time. This approach helps build a comprehensive picture of how patients with this lung cancer subtype are treated and how they fare in usual care settings.

CONDITIONS

Brief Title

Met Non Small Cell Cancer Registry (MOMENT)

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants who signed informed consent form
  • Participants with advanced stage (stages IIIB-IV) NSCLC of any histology
  • Confirmed METex14 skipping alterations by a valid assay
  • Participants starting or already receiving systemic therapy
Not Eligible

You will not qualify if you...

  • Participants currently enrolled in a clinical trial

Research Team

U

US Medical Information

C

Communication Center

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