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Personalized Treatment of Bone and Joint Infections Using Anti-Infective Drugs Based on Drug Levels in Blood and Tissues
Led by Shandong University · Updated on 2024-12-02
300
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are evaluating how to optimize personalized treatment of anti-infective drugs for people with osteoarticular infections by studying drug levels in the blood and tissues. This observational study aims to better understand how these drugs behave in the body using population pharmacokinetics, which can help guide dosing decisions. Participants will receive anti-infective drugs following traditional clinical dosing without additional interventions. The study mainly observes and collects data on drug clearance and distribution over about 30 days. During the study, participants will have their drug exposure measured through blood or tissue samples. Researchers will also monitor markers like erythrocyte sedimentation rate and record any adverse events. The study lasts approximately 30 days to collect all relevant data for analysis.
CONDITIONS
Brief Title
Model-informed Individualized Treatment of Anti-infective Drugs
Research Team
W
Wei Zhao, Ph.D
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