Actively Recruiting

All Genders
Healthy Volunteers
NCT04185935

Molecular Genetics Studies of Cancer Patients and Their Relatives

Led by City of Hope Medical Center · Updated on 2025-06-25

999999

Participants Needed

42

Research Sites

1895 weeks

Total Duration

On this page

Sponsors

C

City of Hope Medical Center

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This trial studies the genetic and behavioral factors that may contribute to the development of specific cancers and how these factors may affect the outcome of the disease in patients with a history of cancer and their relatives.

CONDITIONS

Official Title

Molecular Genetics Studies of Cancer Patients and Their Relatives

Who Can Participate

All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Individuals must have a personal or family history of cancer suggesting inherited predisposition, such as young age at diagnosis, multiple primary cancers, rare tumor types, congenital malformations, family clustering of cancer, or genetic conditions.
  • Participants may be eligible if involved in the City of Hope Cancer Screening & Prevention Program Network or belong to groups with known or suspected increased cancer risk due to genetics or exposure.
  • At least one family member (historian) must be willing to provide information or access to contact relatives for cancer documentation and consent.
  • Individuals under 18 may participate with consent from a legal guardian or parent.
  • Deceased patients may be included through use of public records and archived tissue samples, with consent from next of kin following a specified hierarchy.
Not Eligible

You will not qualify if you...

  • Families are excluded if the designated family historian does not permit access to anyone in the family, preventing accurate verification of family cancer history.

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Trial Site Locations

Total: 42 locations

1

Valleywise Comprehensive Health Center - Phoenix

Phoenix, Arizona, United States, 85008

Actively Recruiting

2

John Muir Medical Center-Concord Campus

Concord, California, United States, 94520

Actively Recruiting

3

City of Hope Medical Center

Duarte, California, United States, 91010

Actively Recruiting

4

Saint Jude Medical Center

Fullerton, California, United States, 92835

Actively Recruiting

5

Saddleback Memorial Medical Center

Laguna Hills, California, United States, 92653

Actively Recruiting

6

USC / Norris Comprehensive Cancer Center

Los Angeles, California, United States, 90033

Actively Recruiting

7

Saint Joseph Hospital - Orange

Orange, California, United States, 92868

Actively Recruiting

8

Sutter Cancer Centers Radiation Oncology Services-Roseville

Roseville, California, United States, 95661

Actively Recruiting

9

Cancer Center of Santa Barbara

Santa Barbara, California, United States, 93105

Actively Recruiting

10

Lynn Regional Cancer Center - West

Boca Raton, Florida, United States, 33428

Actively Recruiting

11

Holy Cross Hospital

Fort Lauderdale, Florida, United States, 33308

Actively Recruiting

12

Kootenai Cancer Center

Post Falls, Idaho, United States, 83854

Actively Recruiting

13

John H Stroger Jr Hospital of Cook County

Chicago, Illinois, United States, 60612

Actively Recruiting

14

Rush University Medical Center

Chicago, Illinois, United States, 60612

Actively Recruiting

15

Mercy Hospital

Cedar Rapids, Iowa, United States, 52403

Actively Recruiting

16

Suburban Hospital

Bethesda, Maryland, United States, 20814

Actively Recruiting

17

Frederick Oncology Hematology Associates

Frederick, Maryland, United States, 21702

Actively Recruiting

18

Steward Saint Elizabeth's Medical Center

Brighton, Massachusetts, United States, 02135

Actively Recruiting

19

Hunterdon Medical Center

Flemington, New Jersey, United States, 08822

Actively Recruiting

20

Lovelace Medical Center-Downtown

Albuquerque, New Mexico, United States, 87102

Actively Recruiting

21

New Mexico Oncology Hematology Consultants

Albuquerque, New Mexico, United States, 87109

Actively Recruiting

22

Presbyterian Kaseman Hospital

Albuquerque, New Mexico, United States, 87110

Actively Recruiting

23

Mount Kisco Medical Group at Northern Westchester Hospital

Mount Kisco, New York, United States, 10549-3417

Actively Recruiting

24

Health Quest Medical Practice PC-Cardio Thoracic

Poughkeepsie, New York, United States, 12601

Actively Recruiting

25

Aultman Health Foundation

Canton, Ohio, United States, 44710

Actively Recruiting

26

Saint Charles Health System

Bend, Oregon, United States, 97701

Actively Recruiting

27

Paoli Memorial Hospital

Paoli, Pennsylvania, United States, 19301

Actively Recruiting

28

Reading Hospital

West Reading, Pennsylvania, United States, 19611

Actively Recruiting

29

The Don and Sybil Harrington Cancer Center

Amarillo, Texas, United States, 79106

Actively Recruiting

30

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center

Houston, Texas, United States, 77030

Not Yet Recruiting

31

Doctor's Hospital of Laredo

Laredo, Texas, United States, 78041

Actively Recruiting

32

Covenant Medical Center

Lubbock, Texas, United States, 79410

Actively Recruiting

33

Saint Agnes Hospital/Agnesian Cancer Center

Fond du Lac, Wisconsin, United States, 54935

Actively Recruiting

34

ProHealth Waukesha Memorial Hospital

Waukesha, Wisconsin, United States, 53188

Actively Recruiting

35

Cheyenne Regional Medical Center-West

Cheyenne, Wyoming, United States, 82001

Actively Recruiting

36

Clinica del Country

Bogotá, Cundinamarca, Colombia

Actively Recruiting

37

Instituto de Cancerologia Las Americas

Medellín, Colombia

Actively Recruiting

38

University of Guadalajara

Guadalajara, Jalisco, Mexico, CP 44340

Actively Recruiting

39

Salvador Zubiran National Institute of Health Sciences and Nutrition

Mexico City, Tlalpan, Mexico, 14080

Actively Recruiting

40

Monterrey Institute of Technology-TecSalud

Nuevo León, Mexico

Actively Recruiting

41

Instituto Nacional de Enfermedades Neoplasicas

Lima, Peru, Lima 34

Actively Recruiting

42

University of Puerto Rico

San Juan, Puerto Rico, 00936

Actively Recruiting

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Research Team

S

Stephen Gruber

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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