Actively Recruiting
Multi-parametric MRI in Patients Suspected for Muscle Invasive Bladder Cancer: a New Local Staging Paradigm
Led by Radboud University Medical Center · Updated on 2026-01-08
360
Participants Needed
19
Research Sites
390 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A two-arm multicenter randomised controlled trial, comparing progression free survival, time to definitive treatment and cost-effectiveness of the standard of care (TURBT) and mpMRI followed by same-day cystoscopic bladder biopsy for diagnosis of patients with suspicion of muscle-invasive bladder cancer.
CONDITIONS
Official Title
Multi-parametric MRI in Patients Suspected for Muscle Invasive Bladder Cancer: a New Local Staging Paradigm
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients 18 years of age or older
- Clinically suspected muscle-invasive bladder cancer
- No lymph node or distant metastases
- Written informed consent provided
You will not qualify if you...
- Unable or unwilling to undergo multi-parametric MRI (mpMRI)
- Unfit for transurethral resection of the bladder tumor (TURBT)
- Unfit for definitive treatment with curative intent
- History of cancer, including bladder cancer, except non-melanoma skin cancer, prostate cancer on active surveillance, or a solid malignant tumor with at least 5 years disease-free since last treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 19 locations
1
Jeroen Bosch ziekenhuis
's-Hertogenbosch, Netherlands
Actively Recruiting
2
Ziekenhuisgroep Twente
Almelo, Netherlands
Actively Recruiting
3
Meander MC
Amersfoort, Netherlands
Not Yet Recruiting
4
Amsterdam UMC, location AMC
Amsterdam, Netherlands
Actively Recruiting
5
Amsterdam UMC, location VUmc
Amsterdam, Netherlands
Actively Recruiting
6
Antoni van Leeuwenhoek - Netherlands Cancer Institute
Amsterdam, Netherlands
Actively Recruiting
7
OLVG
Amsterdam, Netherlands
Actively Recruiting
8
Rijnstate ziekenhuis
Arnhem, Netherlands
Actively Recruiting
9
Maasziekenhuis Pantein
Boxmeer, Netherlands
Actively Recruiting
10
Ziekenhuis Gelderse Vallei
Ede, Netherlands
Actively Recruiting
11
Treant
Emmen, Netherlands
Not Yet Recruiting
12
Medisch Spectrum Twente
Enschede, Netherlands
Not Yet Recruiting
13
St. Antonius ziekenhuis
Nieuwegein, Netherlands
Actively Recruiting
14
Canisius Wilhelmina Ziekenhuis
Nijmegen, Netherlands
Actively Recruiting
15
Radboud university medical center
Nijmegen, Netherlands
Actively Recruiting
16
Erasmus Medical Center
Rotterdam, Netherlands
Not Yet Recruiting
17
Bernhoven ziekenhuis
Uden, Netherlands
Actively Recruiting
18
University Medical Center Utrecht
Utrecht, Netherlands
Actively Recruiting
19
VieCuri medisch centrum
Venlo, Netherlands
Actively Recruiting
Research Team
A
A. G. van der Heijden, Dr.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here