Actively Recruiting
Erosive Tooth Wear, Dentin Hypersensitivity and Associated Risk Factors: An Observational, Cross-Sectional, Multi-Site Epidemiological Study in the U.S.
Led by Indiana University · Updated on 2026-05-05
2500
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
I
Indiana University
Lead Sponsor
H
HALEON
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are conducting an observational, cross-sectional study to investigate the prevalence of erosive tooth wear (ETW) and dentin hypersensitivity (DH) in healthy adults aged 18 and older across five regions in the United States. The study also aims to explore risk factors associated with these dental conditions and compare findings with previous data from Europe and China. Additional goals include assessing gum tissue recession and non-carious cervical lesions. Participants will be recruited from dental school clinics in Indiana, Florida, California, Texas, and North Carolina, with a target of approximately 500 adults per site, balanced by age and gender. During a single study visit, participants will undergo examinations including intra-oral scanning and video recordings during tooth sensitivity testing. Digital images will be analyzed using established indices to assess tooth wear, sensitivity, gum recession, and lesions. Participants will complete questionnaires about demographics and risk factors, and their reactions during sensitivity tests will be recorded. Data collected will be analyzed to understand the frequency and severity of tooth wear and sensitivity, as well as their association with various factors. All assessments occur during one visit, and the study will monitor safety and data quality throughout the process.
CONDITIONS
Brief Title
Multi-site Study to Look at Tooth Wear and Tooth Sensitivity and the Risk Factors Associated.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be aged 18 or over, of any gender
- Be attending a regularly scheduled appointment at a dental school
- Provide voluntary, written informed consent
- Understand and be willing, able, and likely to comply with all study procedures and restrictions
- Be in good health
- Have at least 10 natural teeth (excluding implants, crowns, or bridges)
You will not qualify if you...
- Have any medical condition that could affect safety during the study period, including temporomandibular disorders
- Be unable to respond to questions
- Be an employee or family member of an employee of the study sponsor
- Use maxillary or mandibular orthodontic appliances, except a lingual bar
- Have used pain-relieving drugs or topical analgesics within the past 12 hours
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo a comprehensive single visit where clinical and self-reported data are collected, including intra-oral scanning, tooth wear and sensitivity assessments, and questionnaires on associated risk factors.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Indiana University School of Dentistry - Oral Health Research Institute
Indianapolis, Indiana, United States, 46202
Actively Recruiting
Research Team
A
Anderson Hara, MS, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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