Actively Recruiting
Evaluation of Lower Limb Angiosome Perfusion and Oxygenation Using Thermal and Hyperspectral Imaging
Led by Tampere University · Updated on 2024-06-20
150
Participants Needed
1
Research Sites
22 weeks
Total Duration
On this page
Sponsors
T
Tampere University
Lead Sponsor
T
Tampere University Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating a new way to screen and diagnose chronic limb-threatening ischemia (CLTI), a serious condition affecting blood flow in the lower limbs. This study focuses on examining blood perfusion and oxygen levels in the legs using advanced imaging techniques called hyperspectral and thermal imaging. The study includes both healthy people and those with CLTI to improve understanding of these methods. Participants are divided into three groups: individuals with CLTI, healthy older adults over 50 without cardiovascular diseases, and healthy younger adults aged 18 to 50. The study involves noninvasive imaging procedures that measure blood flow and oxygenation in specific areas of the lower limbs. These imaging sessions last about 45 minutes each. During the study, participants will undergo thermal and hyperspectral imaging of their lower limbs to assess blood perfusion and oxygen levels. Researchers will observe these measurements throughout the procedure. The study aims to gather detailed information on how well these imaging methods can detect changes in limb circulation. Participation time and follow-up details are based on the imaging sessions conducted during the study period.
CONDITIONS
Brief Title
Multimodal Noninvasive Assessment of Peripheral Circulation in Chronic Limb-threatening Ischemia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- For CLTI patients, age over 50 years
- For age control group, age over 50 years and no diagnosis of cardiovascular diseases; ankle-brachial index (ABI) between 0.9 and 1.3
- For healthy group, age between 18 and 50 years and no history of cardiovascular disease
- Volunteering to participate in the study
You will not qualify if you...
- Inability to give informed consent
- Denial to participate
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Approximately 45 minutes per procedure
Participants undergo noninvasive imaging procedures to assess perfusion and oxygenation in the lower limb angiosomes using thermal and hyperspectral imaging.
1 visit (in-person)
Duration - Up to study completion
Participants are observed following the imaging procedures to monitor peripheral circulation over time.
Additional visits may occur depending on cohort assignment
Trial Site Locations
Total: 1 location
1
Tampere University
Tampere, Pirkanmaa, Finland, 33720
Actively Recruiting
Research Team
N
Niku Oksala, MD, PhD, DSc
A
Antti Vehkaoja, DSc
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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