Study of Cardiac MRI to Assess Heart Function in Adults with Severe Mitral Regurgitation Undergoing Robotic Mitral Annuloplasty at Mayo Clinic

What this Trial Is About

Researchers are evaluating a multimodal approach using cardiac CT and MRI to assess the risk of developing left ventricular systolic dysfunction in patients with severe chronic primary mitral regurgitation. This pilot study aims to determine the feasibility of a larger future study focused on this heart condition. The study is observational and sponsored by Mayo Clinic. Adults with severe chronic primary mitral regurgitation who are undergoing robotic mitral annuloplasty at Mayo Clinic Rochester will be included. Each participant will receive two cardiac MRI scans one before surgery and another 6 to 12 months after surgery. Each MRI takes approximately 45 to 60 minutes. The study will observe participants over a two-year period. Participants will be monitored for recruitment and dropout rates, as well as the development of systolic dysfunction during the two years. The study involves consent procedures and MRI scans with and without contrast. Pregnancy status and implantable device compatibility with MRI will be assessed. Data collected will help evaluate left ventricular remodeling and function after the surgical procedure.

Multimodality Evaluation of Left Ventricular Remodeling In Mitral Regurgitation: A Pilot Study