Actively Recruiting

Phase 1
Age: 18Years - 65Years
All Genders
Healthy Volunteers
NCT07421778

A Multiple Ascending Dose Study Evaluating the Safety and Tolerability of a Novel Formulation of QRL-101 in Healthy Participants

Led by QurAlis Corporation · Updated on 2026-02-19

48

Participants Needed

1

Research Sites

30 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

QRL-101-08 is a multiple ascending dose (MAD) study to evaluate the safety, tolerability, and pharmacokinetics (PK) of a novel formulation of QRL-101 in healthy participants.

CONDITIONS

Official Title

A Multiple Ascending Dose Study Evaluating the Safety and Tolerability of a Novel Formulation of QRL-101 in Healthy Participants

Who Can Participate

Age: 18Years - 65Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 65 years inclusive at the time of signing the informed consent
  • Clinical chemistry laboratory values within acceptable range for the population, as per investigator judgment
  • Body mass index of 18 to 32 kg/m2 inclusive
  • Willing and able to practice effective contraception
Not Eligible

You will not qualify if you...

  • Currently enrolled in any other clinical trial involving a study drug, off-label drug or device use, or other medical research incompatible with this study
  • Participation in more than 4 studies a year or participation in a clinical trial within 1 month of the expected dosing date
  • History or presence of medical illness including cardiovascular, hepatic, respiratory, hematological, endocrine, psychiatric, neurological disease, convulsions, or clinically significant laboratory abnormalities that preclude study participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

ICON plc.

Groningen, Netherlands, 9728 NZ

Actively Recruiting

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Research Team

Q

QurAlis Corporation

CONTACT

S

Salah Hadi, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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A Multiple Ascending Dose Study Evaluating the Safety and Tolerability of a Novel Formulation of QRL-101 in Healthy Participants | DecenTrialz