Study on Different Lymph Node Removal Methods for Lung Ground Glass Nodules Smaller Than 3 cm with Over 50% Solid Parts

What this Trial Is About

Researchers are studying the effects of different methods of lymph node removal on the prognosis of small ground glass nodules in the lungs. The nodules involved are less than 3 cm in size and have more than 50% solid components. This study is conducted across multiple centers to better understand the best approach for these cases and is sponsored by Shanghai Zhongshan Hospital. Participants with ground glass nodules that meet the size and composition criteria will be randomly assigned to one of two groups selective lymphadenectomy or systematic lymph node dissection. Both are surgical procedures aimed at removing lymph nodes, but they differ in how extensive the removal is. The study will monitor participants for five years to assess overall survival. During the study, participants will be evaluated through lung CT scans and other clinical assessments to monitor their progress and response to the lymph node removal methods. Researchers will track overall survival over a five-year period to determine which surgical approach may offer better outcomes. Participants will be followed regularly to ensure adherence to the study and track any changes in their condition throughout the study duration, which started in 2020 and is expected to complete by the end of 2028.

A Multiple-center Study on the Effect of Different Ways of Lymph Node Dissection on the Prognosis of Ground Glass Nodules Smaller Than 3cm and With More Than 50% Solid Components