Actively Recruiting

Phase Not Applicable
Age: 65Years +
All Genders
Healthy Volunteers
ID06152211

Using Music-Based Interventions to Improve the Quality of Life and Wellbeing of Older Adults With or at Risk of Alzheimer's Disease

Led by University of Southern California · Updated on 2024-08-02

66

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of music engagement through choir training on hearing, communication, and psychosocial well-being in older adults, particularly those at higher risk of developing dementia such as Alzheimer's disease. This study focuses on adults aged 65 and older, including both carriers and non-carriers of the APOE e4 allele, a known genetic risk factor for late-onset Alzheimer's disease. The study addresses age-related declines in hearing and cognitive function, which are linked to increased dementia risk and social isolation. Participants will be randomly assigned to one of two groups for a 16-week intervention: a community choir program or a group music listening program. The choir group will rehearse weekly for two hours with musical leadership and at-home activities, while the music listening group will meet weekly for two hours to listen to and discuss selected musical recordings. Both activities aim to engage participants socially and cognitively. Throughout the study, participants will undergo assessments including speech-in-noise perception measured by QuickSIN, self-efficacy, interest in life, and loneliness using NIH Toolbox measures. Attendance and engagement will be tracked, and the study will monitor changes over the 16-week period. The total duration of participation aligns with the intervention period, focusing on improving quality of life and well-being in older adults at risk of dementia.

CONDITIONS

Brief Title

Music-Based Interventions, Aging, Alzheimer's Disease

Who Can Participate

Age: 65Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adequate visual and auditory acuity, with correction if necessary
  • Fluency in English to ensure complete testing
  • Age 65 years or older
Not Eligible

You will not qualify if you...

  • Severe hearing loss not correctable with aids
  • History of known neurological or otologic conditions
  • Current severe psychiatric disorders
  • Unstable or serious medical conditions limiting participation
  • Cognitive impairment with MoCA score less than 26
  • Current or past professional music training of 3 or more years, excluding typical educational classes or worship singing

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 16 weeks

Participants attend weekly 2-hour sessions for 16 weeks. They are randomly assigned to either a community choir program with additional at-home music activities or a group music listening program with guided discussions.

Weekly visits for 16 weeks

Trial Site Locations

Total: 1 location

1

University of Southern California

Los Angeles, California, United States, 90089

Actively Recruiting

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Research Team

A

Assal Habibi, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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