Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05651295

A Precision Medicine Approach to Target Engagement for Emotion Regulation

Led by Matthew Southward, PhD · Updated on 2026-05-11

390

Participants Needed

1

Research Sites

169 weeks

Total Duration

On this page

Sponsors

M

Matthew Southward, PhD

Lead Sponsor

N

National Institute of Mental Health (NIMH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The proposed study is designed to first test whether teaching people personalized or standardized emotion regulation skills leads to greater decreases in daily negative emotion intensity. Second, using data from an initial sample, the investigators will prospectively assign an independent sample of participants to receive their predicted optimal or non-optimal skills to determine if it is feasible and efficacious to match participants to the most appropriate training condition. Results of these studies may identify the mechanisms by which emotion regulation interventions impact emotional functioning and allow for the development of personalized, evidence-based, and scalable emotion regulation interventions.

CONDITIONS

Official Title

A Precision Medicine Approach to Target Engagement for Emotion Regulation

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Elevated emotion dysregulation
Not Eligible

You will not qualify if you...

  • Lack of proficiency in English
  • No access to smartphone
  • Conditions requiring greater than outpatient care

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Ohio State University

Columbus, Ohio, United States, 43210

Actively Recruiting

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Research Team

M

Matthew W Southward, Ph.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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A Precision Medicine Approach to Target Engagement for Emotion Regulation | DecenTrialz