Actively Recruiting
A Precision Medicine Approach to Target Engagement for Emotion Regulation
Led by Matthew Southward, PhD · Updated on 2026-05-11
390
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
M
Matthew Southward, PhD
Lead Sponsor
N
National Institute of Mental Health (NIMH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Researchers are evaluating whether teaching people personalized versus standardized emotion regulation skills can better reduce daily negative emotions. The study also aims to see if matching participants to their predicted best skill training is feasible and helpful. This research may reveal how emotion regulation treatments impact emotional health and help develop personalized, evidence-based, and scalable interventions. Participants will be randomly assigned to learn one of three emotion regulation skills—cognitive restructuring, opposite to emotion action, or mindfulness—that matches their personal strengths, or to learn all three skills through interactive videos with surveys to practice and check understanding. These training conditions are designed to compare focused versus broad skill coverage. During the study, participants will report their emotions multiple times daily for 42 days, using the Positive and Negative Affect Schedule-Short Form. They will also complete assessments every two weeks for six weeks, measuring depression, anxiety, personality traits, responses to emotions, and breath-counting tasks. Researchers will monitor changes in emotion regulation effectiveness and emotional experiences to understand the impact of the training.
CONDITIONS
Brief Title
A Precision Medicine Approach to Target Engagement for Emotion Regulation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Elevated emotion dysregulation
You will not qualify if you...
- Lack of proficiency in English
- No access to smartphone
- Conditions requiring greater than outpatient care
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 weeks
Participants learn emotion regulation skills through interactive videos and complete related surveys to practice and understand the skills.
Multiple video sessions over 6 weeks
Duration - 42 to 48 days
Participants provide frequent self-reports on affect and emotion regulation effectiveness using surveys throughout the study period.
7 times daily self-reporting
Trial Site Locations
Total: 1 location
1
Ohio State University
Columbus, Ohio, United States, 43210
Actively Recruiting
Research Team
M
Matthew W Southward, Ph.D.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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