Actively Recruiting
Nanshan Elderly Cohort Study
Led by Sun Yat-sen University · Updated on 2018-06-26
20000
Participants Needed
2
Research Sites
553 weeks
Total Duration
On this page
Sponsors
S
Sun Yat-sen University
Lead Sponsor
S
Shenzhen Nanshan Center for Chronic Disease Control
Collaborating Sponsor
AI-Summary
What this Trial Is About
Objective: The Nanshan Elderly Cohort Study (NECS) aims to investigate the nutritional, as well as other environmental and genetic factors of chronic diseases, such as cardio-metabolic diseases. Study design: NECS is a community-based prospective cohort study. Participants: About 10000-20000 apparently healthy residents, living in Nanshan， Shenzhen (South China) for \>5 years, aged ≥ 65 years, will be recruited between 2018 and 2019. Visits and Data Collection: Participants will be followed up approximately every 3 years by invited to the Community Healthcare Service Centre. At each survey, face-to-face interviews, anthropometric measurements, ultrasonography examination, electrocardiogram test and specimen collection will be conducted. Key variables: 1. Face-to-face interviews: Structured questionnaires will be used to collect the participants' socio-demographic characteristics, lifestyles, habitual dietary intake, physical activity, history of chronic diseases, use of supplements and medications, family history, psychological health and cognitive function. 2. Physical examinations: Anthropometric measurements, blood pressure tests, handgrip strength, and usual gait speed. 3. Ultrasonography examinations: Ultrasonography examination will be performed to determine carotid artery intima-media thickness and plaque, fatty liver. 4. Electrocardiogram test: Electrocardiogram test is to obtain information about the structure and function of the heart. 5. Specimen collections: Overnight fasting blood sample, early morning first-void urine sample and faeces samples will be collected and stored at -80°C till tests. 6. Laboratory tests: 1. Blood tests: Metabolic syndrome-related indices; nutritional indices; inflammatory markers; sexual hormones; genetic markers. 2. Urinary tests: Flavonoids and flavones, minerals, creatinine and renal function related markers. 3. Fecal test: Gut microbiota and related metabolites. 7. Morbidity and mortality: Relevant data will be also retrieved via local multiple Health information systems. 8. Others: Many other laboratory tests or instrument tests will be developed depended on needs and resources in future.
CONDITIONS
Official Title
Nanshan Elderly Cohort Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 65 years or older
- Living in Nanshan, Shenzhen for at least 5 years
- Chinese ethnicity
You will not qualify if you...
- History of hospital-confirmed diabetes, heart, liver, or kidney failure, cancer, or cardiovascular disease events
- Following a special diet due to disease or weight control
- Mental or physical disability
- Likely to move to another city within 5 years
- Unwilling to participate in any survey or sample collection
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
Department of Non-communicable Disease Prevention and Control, Shenzhen Nanshan Center for Chronic Disease Control
Shenzhen, Guangdong, China, 518054
Actively Recruiting
2
Department of Medical Statistics & Epidemiology, School of Public Health, Sun Yat-sen University
Guangzhou, China, 510080
Withdrawn
Research Team
Y
Yuming Chen
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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