Actively Recruiting

Age: 5Years - 18Years
All Genders
Healthy Volunteers
NCT05982847

National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South Africa

Led by North-West University, South Africa · Updated on 2026-04-07

22464

Participants Needed

11

Research Sites

243 weeks

Total Duration

On this page

Sponsors

N

North-West University, South Africa

Lead Sponsor

M

Medical Research Council, South Africa

Collaborating Sponsor

AI-Summary

What this Trial Is About

The Childhood Hypertension Consortium of South Africa (CHCSA) was established to foster relationships between the healthcare sector and schools through community engagement and outreach as well as contributing to the decolonization of normative paediatric blood pressure reference values. To date, there has been no nation-wide project in South Africa to determine nationally representative normal blood pressure reference values, nor to estimate the true prevalence of hypertension in the paediatric population of the country. This study will provide critical information on the understanding of blood pressure and hypertension in children, especially of African ancestry. Not only will this effort contribute to the development of the first nationally representative normal reference values of blood pressure but will also benefit healthcare providers in the sector with a clear guideline on the management of high blood pressure in children as developed by experts working with these challenges daily.

CONDITIONS

Official Title

National Blood Pressure Screening in Children to Improve Paediatric Healthcare in South Africa

Who Can Participate

Age: 5Years - 18Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Children between 5 and under 18 years old
  • Voluntary assent from the child and permission from a parent or guardian
Not Eligible

You will not qualify if you...

  • Inability to give informed consent due to comprehension or language barriers
  • Children who do not assent or whose parents do not consent to participate
  • Use of drugs, alcohol, or tobacco products that interfere with study participation
  • Age under 5 years or 18 years and older
  • Use of medications or presence of diseases (e.g., chronic kidney or heart disease) that affect blood pressure, leading to exclusion from analysis for normative values

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 11 locations

1

Walter Sisulu University

Mthatha, Eastern Cape, South Africa

Not Yet Recruiting

2

Nelson Mandela Metropolitan University

Port Elizabeth, Eastern Cape, South Africa

Actively Recruiting

3

University of the Free State

Bloemfontein, Free State, South Africa

Actively Recruiting

4

University of the Witwatersrand

Johannesburg, Gauteng, South Africa

Actively Recruiting

5

University of KwaZulu-Natal

Durban, KwaZulu-Natal, South Africa

Not Yet Recruiting

6

University of Limpopo

Polokwane, Limpopo, South Africa

Not Yet Recruiting

7

Hypertension in Africa Research Team (HART), North-West University

Potchefstroom, North West, South Africa, 2531

Actively Recruiting

8

Red Cross War Memorial Children Hospital

Cape Town, Western Cape, South Africa

Not Yet Recruiting

9

South African Medical Research Council

Cape Town, Western Cape, South Africa

Not Yet Recruiting

10

University of Cape Town

Cape Town, Western Cape, South Africa

Not Yet Recruiting

11

University of Zurich

Zurich, Switzerland

Not Yet Recruiting

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Research Team

R

Ruan Kruger, PhD

CONTACT

L

Lebo F Gafane-Matemane, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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