Actively Recruiting

Age: 2Years - 35Years
All Genders
NCT07464821

National Multicentre Study on Lipid Profile in Noonan Syndrome and Related Disorders: Trends by Age, Gender and Genotype

Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2026-03-11

200

Participants Needed

14

Research Sites

112 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

RASopathies, including Noonan syndrome, involve dysmorphisms, metabolic alterations, and an unfavorable lipid profile. This study investigates lipid and glucose metabolism to improve patient care.

CONDITIONS

Official Title

National Multicentre Study on Lipid Profile in Noonan Syndrome and Related Disorders: Trends by Age, Gender and Genotype

Who Can Participate

Age: 2Years - 35Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinically diagnosed RASopathy confirmed by molecular testing
  • Patients referred to participating centers between 01/01/2001 and 31/12/2022
  • Age at enrollment between 2 and 35 years, inclusive
  • Obtaining informed consent
Not Eligible

You will not qualify if you...

History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 14 locations

1

Azienda Ospedaliero-Universitaria di Alessandria

Alessandria, Italy

Not Yet Recruiting

2

AOU Policlinico di Bari

Bari, Italy

Not Yet Recruiting

3

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, Italy

Actively Recruiting

4

AOU Meyer IRCCS

Florence, Italy

Actively Recruiting

5

IRCCS Istituto Giannina Gaslini

Genova, Italy

Actively Recruiting

6

AOU Policlinico G. Martino

Messina, Italy

Not Yet Recruiting

7

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Milan, Italy

Not Yet Recruiting

8

IRCCS Ospedale San Raffaele

Milan, Italy

Not Yet Recruiting

9

Azienda Ospedaliera Policlinico di Modena

Modena, Italy

Not Yet Recruiting

10

Fondazione IRCCS San Gerardo dei Tintori

Monza, Italy

Not Yet Recruiting

11

AOU Vanvitelli

Naples, Italy

Not Yet Recruiting

12

Azienda Ospedale-Università di Padova

Padova, Italy

Not Yet Recruiting

13

Azienda Ospedaliero-Universitaria di Parma

Parma, Italy

Not Yet Recruiting

14

AOUI-VR Azienda Ospedaliero-Universitaria Integrata di Verona

Verona, Italy

Not Yet Recruiting

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Research Team

F

Federica Tamburrino

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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National Multicentre Study on Lipid Profile in Noonan Syndrome and Related Disorders: Trends by Age, Gender and Genotype | DecenTrialz