Actively Recruiting

Age: 18Years - 70Years
FEMALE
Healthy Volunteers
NCT05845333

Neurocognitive Abnormalities in Stimulant Abuse Among High-Risk Women

Led by The Mind Research Network · Updated on 2025-05-08

334

Participants Needed

1

Research Sites

252 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Substance use disorders and psychopathy are serious and costly mental health issues. Psychopathy is known to be associated with aberrant moral decision making and there is considerable interest in determining whether substance use disorders lead to impairments in these same cognitive processes. Recent large-scale research initiatives in forensic settings have begun to identify substance abuse and psychopathy-related disruption in the neural mechanisms involved in moral decision-making processes, and associations between these neural networks and future relapse and antisocial behavior. Here the investigators extend prior work (with incarcerated men) to examine these issues among incarcerated women in order to better understand sex differences. This project addresses the overall lack of neurocognitive research in criminal offenders with substance use disorders, thereby focusing on a major public health issue in an underserved and understudied population.

CONDITIONS

Official Title

Neurocognitive Abnormalities in Stimulant Abuse Among High-Risk Women

Who Can Participate

Age: 18Years - 70Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Biological sex is female
  • Intelligence Quotient 70 or higher
  • Reading level 5th grade or higher
  • Able to speak and understand English
Not Eligible

You will not qualify if you...

  • Uncorrectable auditory or visual deficits
  • Currently pregnant
  • MRI contraindication
  • Central nervous system disease
  • Current major medical condition
  • Hypertension with complications (e.g., stroke)
  • Diabetes with complications
  • Lifetime history of psychotic disorder
  • Self-report of psychotic disorder (with psychiatric hospitalization) in first degree relative
  • Drug use in past three months
  • (Healthy controls only): History of arrest
  • (Healthy controls only): Substance use beyond light alcohol or marijuana use
  • (Healthy controls only): Currently taking psychotropic medications

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Mind Research Network

Albuquerque, New Mexico, United States, 87106

Actively Recruiting

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Research Team

C

Carla Harenski

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

7

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